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首页> 外文期刊>International Journal of Reproduction, Contraception, Obstetrics and Gynecology >A study of effect of oral PGE1 and cervical PGE2 on induction of labor and mode of delivery
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A study of effect of oral PGE1 and cervical PGE2 on induction of labor and mode of delivery

机译：口服PGE1和宫颈PGE2对引产和分娩方式的影响研究

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Background: Induction of labor is one of the most important procedures done by the Obstetricians. Induction of labor with the help of prostaglandins offer the advantage of promoting cervical ripening along with stimulating the contractility of the myometrium. Methods: 200 pregnant women with singleton pregnancy both nulliparous and multiparous, were included in the study at term gestation (39weeks) with Bishop’s score 6, and reactive NST. The subjects were divided in to two groups Group A including patients who were given oral PGE1 - 50 mcg Tab, and Group B with cervical PGE2, 0.5 mg, gel. The outcome indicators were recorded in both Group A and Group B and analyzed. The mean time taken from induction to vaginal delivery in Group A was 628±67 minutes and in Group B was 839±118 minutes. Incidence of LSCS in Group B when compared to Group A (p value 0.005). Results: Incidence of LSCS in Primi’s in Group B compared to Primi’s in Group A was statistically significant (p value 0.009). Non-progression of labor was observed to be the major indication for LSCS in Group B. Meconium stained labor was found to be the major indication for LSCS in Group A. Conclusions: The study concludes that using 50 mcg oral misoprostol, is an effective and safe mode of induction of labor in comparison to PGE2 gel. Vaginal deliveries are more with the use of oral misoprostol and the induction to delivery interval is also lesser than that in cervical PGE2 use.
机译：背景：引产是妇产科医生最重要的程序之一。在前列腺素的帮助下引产具有促进子宫颈成熟以及刺激子宫肌层收缩的优点。方法：本研究纳入200名原胎和多胎单胎妊娠孕妇，足月妊娠（> 39周），Bishop得分<6，反应性NST。将受试者分为两组，分别为口服PGE1-50 mcg Tab的患者和B组宫颈PGE2（0.5 mg，凝胶）的患者。结果指标记录在A组和B组中并进行分析。 A组从诱导到阴道分娩的平均时间为628±67分钟，B组为839±118分钟。与A组相比，B组中LSCS的发生率（p值<0.005）。结果：与A组的Primi相比，B组的Primi的LSCS发生率具有统计学意义（p值0.009）。观察到分娩不进展是B组LSCS的主要指征。发现胎粪污染的劳工是A组LSCS的主要指征。结论：研究得出结论，使用50 mcg口服米索前列醇是一种有效且有效的方法。与PGE2凝胶相比，安全的引产方式。口服米索前列醇可使阴道分娩更多，并且分娩间隔的诱导也比宫颈PGE2少。

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