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Survival Analysis of Tuberculosis Patients in Upper West Region of Ghana

机译:加纳上西部地区结核病患者的生存分析

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A study of survival rate of TB patients was carried out using secondary data extracted from 85 Tb patients’ records from January 2013 to December 2014 in the Upper West region of Ghana. The Cox Proportional Hazard Model was used to determine the components of the model. Apart from the time to event such as death, each Tb patient had a number of risk factors (covariates) which affected either survival or mortality. The study sought to determine the effect of three factors or covariates on survivorship. The baseline was determined as; a female aged between 0-24 years, who had negative smear TB and was tested negative for HIV and had not started TB treatment. Of all the covariates, TB/HIV co-infection was found to be the most influential covariate or factor that affected the hazard rate or force of mortality. In contrast, Tb treatment was observed to have had significant influence on survivorship. The Cox model therefore provided an estimate of the relative level of an individual’s survivorship in relation to the baseline. Mortality or survival differences occurred as a result of each patient’s predisposing factors such as sex, age, type of TB, co-infection with HIV amongst others.
机译:使用从2013年1月至2014年12月在加纳上西部地区的85例Tb患者记录中提取的辅助数据,对TB患者的生存率进行了研究。使用Cox比例危害模型确定模型的组成部分。除了死亡之类的事件发生时间外,每位Tb患者都有许多影响生存或死亡的危险因素(协变量)。该研究试图确定三个因素或协变量对生存率的影响。基准确定为:一名0-24岁的女性,其涂片结核阴性,经检测HIV阴性,尚未开始结核治疗。在所有协变量中,发现结核病/ HIV合并感染是影响危险率或死亡率的最有影响的协变量或因素。相反,观察到Tb治疗对生存率有重要影响。因此,Cox模型提供了相对于基准的个人生存水平的相对估计。死亡率或生存差异是由每个患者的易患因素引起的,这些因素包括性别,年龄,结核病类型,HIV合并感染等。

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