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首页> 外文期刊>Intestinal research. >Characteristics and outcomes of endoscopically resected colorectal cancers that arose from sessile serrated adenomas and traditional serrated adenomas
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Characteristics and outcomes of endoscopically resected colorectal cancers that arose from sessile serrated adenomas and traditional serrated adenomas

机译：无柄锯齿状腺瘤和传统锯齿状腺瘤引起的内镜切除结直肠癌的特征和结局

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Background/Aims The efficacy and safety of endoscopic resection of colorectal cancer derived from sessile serrated adenomas or traditional serrated adenomas are still unknown. The aims of this study were to verify the characteristics and outcomes of endoscopically resected early colorectal cancers developed from serrated polyps. Methods Among patients who received endoscopic resection of early colorectal cancers from 2008 to 2011, cancers with documented pre-existing lesions were included. They were classified as adenoma, sessile serrated adenoma, or traditional serrated adenoma according to the baseline lesions. Clinical characteristics, pathologic diagnosis, and outcomes were reviewed. Results Overall, 208 colorectal cancers detected from 198 patients were included: 198 with adenoma, five with sessile serrated adenoma, and five with traditional serrated adenoma. The sessile serrated adenoma group had a higher prevalence of high-grade dysplasia (40.0% vs. 25.8%, P Conclusions Cautious observation and early endoscopic resection are recommended when colorectal cancer from serrated polyp is suspected. Colorectal cancers from serrated polyp can be treated successfully with endoscopy.
机译：背景/目的内镜切除无固定锯齿状腺瘤或传统锯齿状腺瘤的结直肠癌的疗效和安全性尚不清楚。这项研究的目的是验证由锯齿状息肉形成的内镜切除的早期结直肠癌的特征和结局。方法在2008年至2011年接受内镜切除的早期大肠癌患者中，包括已记录有既往病变的癌症。根据基线病变将其分为腺瘤，无蒂锯齿状腺瘤或传统锯齿状腺瘤。回顾了临床特征，病理诊断和结果。结果总体上，从198例患者中检测到208例大肠癌：198例患有腺瘤，5例患有无蒂锯齿状腺瘤和5例患有传统锯齿状腺瘤。无柄锯齿状腺瘤组发生高度异型增生的几率较高（40.0％vs. 25.8％，P）结论当怀疑锯齿状息肉的结直肠癌被怀疑时，建议谨慎观察并尽早进行内镜切除术。内窥镜检查。

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