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首页> 外文期刊>Intestinal research. >Visceral Fat as a Useful Parameter in the Differential Diagnosis of Crohn's Disease and Intestinal Tuberculosis
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Visceral Fat as a Useful Parameter in the Differential Diagnosis of Crohn's Disease and Intestinal Tuberculosis

机译：内脏脂肪是克罗恩病和肠结核鉴别诊断的有用参数

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Background/Aims Because of the similarities in the clinical presentations of Crohn's disease (CD) and intestinal tuberculosis (ITB), differential diagnosis is critical. Mesenteric adipose tissue hypertrophy and creeping fat are characteristic features of CD. The purpose of this study was to assess the usefulness of visceral fat for the differential diagnosis of CD and ITB. Methods We conducted a retrospective review of 50 patients with findings of CD or ITB between January 2005 and July 2008. Abdominal computed tomography (CT) was performed on all subjects during their first evaluation. The abdominal fat area was assessed using quantitative abdominal CT. Results The ratio of visceral fat to total fat (VF/TF) was significantly higher in male CD patients than in male ITB patients. The ratio of visceral fat to subcutaneous fat (VF/SF) was also higher in CD patients than in patients with ITB. For a VF/TF cut-off value of 0.46, the sensitivity and specificity for the diagnosis of CD were 42.1% and 93.3% respectively, with positive and negative predictive values of 88.9% and 56.0%, respectively. Conclusion Measurement of the abdominal fat area using CT can be clinically useful for the differential diagnosis of CD and ITB.
机译：背景/目的由于克罗恩病（CD）和肠结核（ITB）在临床表现上的相似性，鉴别诊断至关重要。肠系膜脂肪组织肥大和脂肪fat行是CD的特征。这项研究的目的是评估内脏脂肪在CD和ITB鉴别诊断中的作用。方法我们回顾性回顾了2005年1月至2008年7月间50例CD或ITB表现的患者。在所有受试者的首次评估期间均进行了腹部计算机断层扫描（CT）。使用定量腹部CT评估腹部脂肪区域。结果男性CD患者的内脏脂肪与总脂肪之比（VF / TF）明显高于男性ITB患者。 CD患者的内脏脂肪与皮下脂肪的比率（VF / SF）也高于ITB患者。 VF / TF截断值为0.46时，CD诊断的敏感性和特异性分别为42.1％和93.3％，阳性和阴性预测值分别为88.9％和56.0％。结论CT测量腹部脂肪区域可用于CD和ITB的鉴别诊断。

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