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Colorectal Liver Metastases

机译:结直肠肝转移

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摘要

The diagnosis and management of CRLM is complex and requires a multidisciplinary team approach for optimal outcomes. Over the past several decades, the 5-year survival following resection of CRLM has increased and the criteria for resection have broadened substantially. Even patients with multiple, bilateral CRLM, previously thought unresectable, may now be candidates for resection. Two-stage hepatectomy, repeat curative-intent hepatectomy, and even selected resection of extrahepatic metastases have further increased the number of patients who may be treated with curative intent. Multiple liver-directed therapies exist to treat unresectable, incurable patients with adequate survival benefit and morbidity rates.
机译:CRLM的诊断和管理非常复杂,需要多学科的团队合作才能获得最佳结果。在过去的几十年中,CRLM切除后的5年生存期增加了,切除标准也大大扩大了。甚至以前被认为无法切除的多发性双侧CRLM患者现在也可以进行切除。两阶段肝切除术,反复进行根治性肝切除术,甚至选择切除肝外转移灶,都进一步增加了可能接受根治性治疗的患者人数。存在多种肝定向疗法,以治疗具有足够的生存获益和发病率的不可切除的,无法治愈的患者。

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