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首页> 外文期刊>Iranian journal of public health. >Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran
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Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran

机译:伊朗北部单纯疱疹病毒1型和2型的血清流行病学

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Background:Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran. The aim of this study was to determine the seroprevalence of HSV type 1 and 2 based on age, gender, marital status, education, living area, job, symptoms and history of disease variables.Methods:The study population included 800 randomly selected persons from laboratories in Gilan Province, Iran, from 2010 to 2011. Demographic data gathered by a well-designed questionnaire and for serological studies, blood samples were collected and centrifuged. ELISA HSV-1, 2 and HSV-2 specific ELISA kits were used to determine IgG type specific antibodies in sera samples. Person’s chi-square test was applied to compare HSV-1 and HSV-2 seropositivities.Results:HSV-1 and HSV-2 IgG antibodies were positive in 467 (58.4%) and 28 (3.5%) subjects, respectively. There was significant correlation between age, marital status, job, symptoms, history of disease and HSV seroprevalence (P<0.05).Conclusion:Our findings were in agreement with prior studies in which HSV-1 infections was more prevalent than HSV-2 and seropositivity increased with age.
机译:背景:1型和2型单纯疱疹病毒(HSV)是全球常见的传染原。在亚洲,特别是在伊朗,HSV-1和HSV-2感染的流行率数据有限。这项研究的目的是根据年龄,性别,婚姻状况,教育程度,生活区域,工作,症状和疾病变量历史来确定1型和2型HSV的血清流行率。方法:研究人群包括800名从中随机选择的人2010年至2011年,在伊朗吉兰省的实验室中进行研究。通过精心设计的调查表收集的人口统计数据并进行血清学研究,然后收集血液样本并进行离心。 ELISA HSV-1、2和HSV-2特异性ELISA试剂盒用于确定血清样品中的IgG型特异性抗体。应用卡方检验比较HSV-1和HSV-2血清阳性。结果:HSV-1和HSV-2 IgG抗体分别在467(58.4%)和28(3.5%)个受试者中呈阳性。年龄,婚姻状况,工作,症状,病史和HSV血清阳性率之间存在显着相关性(P <0.05)。结论:我们的发现与先前的研究相吻合,在先前的研究中,HSV-1感染比HSV-2感染更普遍,血清阳性随年龄增加。

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