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首页> 外文期刊>Iranian journal of pediatrics >Iron Deposition in Duodenal Mucosa; a Review and Report of Three Cases in Pediatric Age Group
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Iron Deposition in Duodenal Mucosa; a Review and Report of Three Cases in Pediatric Age Group

机译：十二指肠粘膜中的铁沉积;儿科三例回顾与报告

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BackgroundFerrous sulfate drops are routinely used in Iran in infants older than 6 months of age. Effect of ferrous sulfate drops in preventive or therapeutic doses on gastrointestinal mucosa of infants is not studied as yet. Upper gastrointestinal complications due to acute iron poisoning are well known in this age group. In this article, we reviewed published articles on iron deposition in upper gastro-intestinal tract and also introduce clinical, endoscopic and histological findings in three cases with iron deposition in duodenal mucosa.Cases PresentationWe encountered three cases of iron deposition in duodenal mucosa among about 8000 biopsies during a 10 year period which is a very low incidence despite routine use of iron supplement in children above 6 months of age in this country. One of our cases suffered from steatorrhea and another from failure to thrive, which raises concern about effects of iron deposition in small intestine.ConclusionThe clinical significance and effects of iron deposition in pediatric age group is yet to be elucidated. Iron deposition as a solitary finding is not reported in duodenal biopsies of infants as yet. Since iron supplement is widely used in this age group, it is justified to consider its deposition and possible effects on absorption.
机译：背景技术在伊朗，通常在6个月以上的婴儿中使用硫酸亚铁滴剂。尚未研究预防或治疗剂量的硫酸亚铁滴对婴儿胃肠道粘膜的影响。在这个年龄段，由于急性铁中毒引起的上消化道并发症是众所周知的。在本文中，我们回顾了有关上消化道铁沉积的文章，并介绍了3例十二指肠粘膜中铁沉积的临床，内镜和组织学发现。病例介绍我们在8000例中遇到了3例十二指肠粘膜中的铁沉积。尽管该国6个月以上的儿童常规使用铁补充剂，但10年的活检率非常低。我们中的一例患有脂肪泻，另一例由于衰竭而无法壮成长，这引起了人们对小肠铁沉积的影响的关注。结论小儿铁质沉积的临床意义和影响尚待阐明。迄今为止，尚未在婴儿的十二指肠活检中报告铁沉积是一个单独的发现。由于铁补充剂广泛用于这一年龄组，因此有理由考虑铁的沉积以及对吸收的可能影响。

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