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首页> 外文期刊>Italian Journal of Medicine >Asymptomatic superior mesenteric vein thrombosis as unusual complication of acute cytomegalovirus infection: a case report
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Asymptomatic superior mesenteric vein thrombosis as unusual complication of acute cytomegalovirus infection: a case report

机译：无症状的肠系膜上静脉血栓形成为急性巨细胞病毒感染的异常并发症：一例报告

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We describe a 39-year-old male who presented with a fever of unknown origin, the diagnostic work-up of which disclosed an acute cytomegalovirus (CMV) infection complicated by a partial superior mesenteric vein (SMV) thrombosis. Further investigations revealed the presence of factor V Leiden mutation. Oral anticoagulant treatment with warfarin led to a complete recanalization of SMV two months after. A literature review on the association between CMV infection and portal system (PS) thrombosis in immunocompetent patients was performed. We found that, in agreement with our case, in a minority of case reports patients did not complain of abdominal pain, but presented with a mononucleosis-like syndrome with malaise and prolonged fever and displayed a variable elevation of aminotransferase levels. Interestingly, most of them exhibited a limited extension of portal thrombosis. On the whole, these data suggest that PS thrombosis during acute CMV infection may be an underestimated complication.
机译：我们描述了一个39岁的男性，他出现了来历不明的发烧，其诊断结果显示了急性巨细胞病毒（CMV）感染并发部分肠系膜上静脉（SMV）血栓形成。进一步的调查表明存在因子V莱顿突变。华法林口服抗凝治疗导致两个月后SMV完全再通。文献综述了免疫功能正常的患者中巨细胞病毒感染与门静脉系统血栓形成之间的关系。我们发现，与我们的病例一致，在少数病例报告中，患者并未抱怨腹痛，而是表现为单核细胞增多症样症状，全身乏力和持续发烧，并且氨基转移酶水平升高。有趣的是，其中大多数都表现出门脉血栓形成的有限扩展。总体而言，这些数据表明急性CMV感染期间PS血栓形成可能是被低估的并发症。

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