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首页> 外文期刊>Italian journal of pediatrics >Epidemiology and associations with climatic conditions of Mycoplasma pneumoniae and Chlamydophila pneumoniae infections among Chinese children hospitalized with acute respiratory infections
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Epidemiology and associations with climatic conditions of Mycoplasma pneumoniae and Chlamydophila pneumoniae infections among Chinese children hospitalized with acute respiratory infections

机译:中国住院急性呼吸道感染儿童的肺炎支原体和肺炎衣原体感染的流行病学及其与气候条件的关系

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Background The incidence of severe acute respiratory tract infections in children caused by Mycoplasma pneumoniae (syn. Schizoplasma pneumoniae) and Chlamydophila pneumoniae (formerly Chlamydia pneumoniae) varies greatly from year to year and place to place around the world. This study investigated the epidemiology of M. pneumoniae and C. pneumoniae infections among children hospitalized with acute respiratory infections in Suzhou, China in the year 2006, and associations between incidence rates and climatic conditions. Methods Nasopharyngeal aspirates obtained from 1598 patients (aged 26.4?±?28.3 months; range, 1 month to 13 years) were analyzed with real-time PCR and ELISA. Meteorological data were obtained from the weather bureau. Results About 18.5% of patients were infected with M. pneumoniae and, C. pneumoniae, or both. Isolated M. pneumoniae infection was positively correlated with increasing age (χ2?=?34.76, P?
机译:背景技术由肺炎支原体(肺炎支原体)和肺炎衣原体(以前称为肺炎衣原体)引起的儿童严重急性呼吸道感染的发生率每年都在世界各地变化很大。这项研究调查了2006年在中国苏州住院的患有急性呼吸道感染的儿童中肺炎支原体和肺炎衣原体的流行病学,以及发病率与气候条件之间的关系。方法采用实时荧光定量PCR和ELISA法对1598例26.4±28.3个月的鼻咽抽吸物进行分析。气象数据是从气象局获得的。结果约18.5%的患者感染了肺炎支原体和/或肺炎衣原体。分离的肺炎支原体感染与年龄的增加呈正相关(χ2= 34.76,P <0.0001)。肺炎支原体感染的发病率是季节性的,在夏季达到峰值(P 0.0001),在冬季达到最低(P <= 0.0001),而肺炎衣原体的感染仅在秋季低(P <= 0.02)。每月平均温度与肺炎支原体感染的发生率密切相关(r = 0.825,P = 0.001)。结论肺炎支原体和肺炎衣原体是住院急性呼吸道感染儿童的重要传染原。肺炎支原体感染显示与环境温度密切相关。

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