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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women
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Distinguishing between primary infection and reinfection with rubella vaccine virus by IgG avidity assay in pregnant women

机译：通过IgG亲和力分析区分孕妇的原发感染和再感染风疹疫苗病毒

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摘要

During the mass measles/rubella vaccination campaign in 2003 in Iran, many pregnant women were vaccinated mistakenly or became pregnant within 1 month of vaccination. To distinguish pregnant women who were affected by rubella vaccine as primary infection from those who had rubella reinfection from the vaccine, serum samples were collected 1–3 months after the campaign from 812 pregnant women. IgG avidity assay showed that 0.3% of the women had no rubella-specific IgG response; 14.4% had low-avidity anti-rubella IgG and were therefore not immune to rubella before vaccination; 85.3% had high-avidity anti-rubella IgG and were regarded as cases of reinfection.
机译：在2003年的伊朗大规模麻疹/风疹疫苗接种运动中，许多孕妇在接种疫苗后1个月内错误接种了疫苗或怀孕。为了区分受风疹疫苗感染为主要感染的孕妇和再次受风疹疫苗感染的孕妇，在运动后1-3个月收集了812名孕妇的血清样本。 IgG亲和力测定显示0.3％的女性没有风疹特异性IgG反应; 14.4％的人有低抗风疹IgG抗体，因此在接种疫苗之前对风疹没有免疫; 85.3％的患者具有高抗风疹IgG抗体，被视为再感染病例。

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