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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Study of methacholine positivity in patients with chronic cough at Masih Daneshvari hospital, Tehran, 2007–2008
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Study of methacholine positivity in patients with chronic cough at Masih Daneshvari hospital, Tehran, 2007–2008

机译：2007–2008年在德黑兰Masih Daneshvari医院进行的慢性咳嗽患者乙酰甲胆碱阳性研究

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摘要

While airways reactivity is among the characteristics of asthma, it is not considered a sufficient condition diagnostically and the methacholine challenge is a non-specific diagnostic aid in cases of chronic cough and reactive airways disease. The aim of this cross-sectional study was to determine the metacholine response positivity and diagnosis of asthma in patients with chronic cough presenting to a hospital in Tehran during 2007 and 2008. Of 101 patients with chronic cough (with no history of sinusitis, recent pulmonary infection, bronchitis, gasteroesophageal reflux or underlying pulmonary conditions), 51.5% showed reactive airways disease to the methacholine test, 40.6% were unreactive and 7.9% were indeterminate. A positive methacholine challenge test was positively correlated with new wheezing. Although the methacholine challenge test is not a primary test for evaluating chronic cough, if no other reason for chronic cough is found, it may be a guiding test for asthma.
机译：虽然气道反应性是哮喘的特征之一，但在诊断上尚不足以诊断为哮喘，并且在慢性咳嗽和反应性气道疾病的情况下，乙酰甲胆碱的挑战是非特异性的诊断辅助手段。这项横断面研究的目的是确定2007年至2008年在德黑兰一家医院就诊的慢性咳嗽患者的胆碱反应阳性和哮喘的诊断。在101例慢性咳嗽患者（无鼻窦炎史，近期肺感染，支气管炎，胃食管反流或潜在的肺部疾病）中，有51.5％的乙酰甲胆碱试验显示为反应性气道疾病，40.6％的患者无反应，7.9％的患者不确定。乙酰甲胆碱激发试验阳性与新发喘息呈正相关。尽管乙酰甲胆碱激发试验不是评估慢性咳嗽的主要方法，但如果未发现其他引起慢性咳嗽的原因，则可能是哮喘的指导性测试。

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