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首页> 外文期刊>Eastern Journal of Medicine >Diagnostic difficulty in macroscopically invisible cervical adenocarcinoma: Case report
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Diagnostic difficulty in macroscopically invisible cervical adenocarcinoma: Case report

机译：肉眼看不见的宫颈腺癌的诊断困难：病例报告

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Diagnostic difficulty in macroscopically invisible cervical adenocarcinoma: Case report Nermin Koc 1 , Selcuk Ayas 2 , Davut Sahin 1 , Suna Cesur 1 , Lütfiye Uygur 3 1 2 3 Cervical adenocarcinomas are the second most common malignant tumours of the cervix after squamous cell carcinoma. Their frequency is reported to be gradually increasing. These tumours are polypoid or papillary in 50%, diffuse or nodular in 15%, and occult (cannot be observed macroscopically) in 10-15% of the cases. We present the pathological features of three cervical adenocarcinoma cases that could not be observed macroscopically but were found by endocervical curettage. Cervicovaginal smears of the cases were prepared by conventional methods and PAP stained. Endocervical curettage and resection materials were reexamined. One patient?s smear material could not be found. No positive findings were detected in the smears of other two cases. The carcinomas could be determined with endocervical curettage in all three cases. All cervixes were sampled and the tissues were processed as the tumour could not be seen macroscopically in hysterectomy materials. Clear cell carcinoma was diagnosed in one case and endocervical mucinous adenocarcinoma in the other two cases. Cervical adenocarcinomas can be occult in some cases and can not be observed during macroscopic examination as in our cases. A large number of paraffin-embedded blocks should be prepared, and if necessary, all cervixes should be processed to find the tumor in such cases. The possibility of diagnosing the tumors which cannot be seen macroscopically and cannot be determined clinically increases if the number of samples taken from the cervix is increased in hysterectomy materials and if conization can be performed after positive ECC which properly performed before endometrial sampling.
机译：肉眼看不见的子宫颈腺癌的诊断困难：病例报告Nermin Koc 1 ，Selcuk Ayas 2 ，Davut Sahin 1 ，Suna Cesur 1 < / sup>，LütfiyeUygur 3 1 2 3 宫颈腺癌是宫颈第二大最常见的恶性肿瘤鳞状细胞癌后。据报道，它们的频率正在逐渐增加。这些肿瘤为多发性或乳头状，占50％，弥漫性或结节性，占15％，隐匿性（无法从肉眼观察到）占10-15％。我们介绍了三个宫颈腺癌病例的病理学特征，这些病例在肉眼观察不到，但通过宫颈刮除术发现。通过常规方法制备宫颈阴道涂片并进行PAP染色。再次检查宫颈刮除术和切除材料。找不到一名患者的涂片材料。在其他两个病例的涂片中未发现阳性结果。在这三例病例中均可以通过宫颈刮宫术来确定癌变。对所有子宫颈进行取样，并对组织进行处理，因为在子宫切除术材料中肉眼看不到肿瘤。其中1例被诊断为透明细胞癌，另2例被诊断为宫颈内粘液性腺癌。宫颈腺癌在某些情况下可能是隐匿性的，而在我们的病例中，在肉眼检查时无法观察到。应准备大量石蜡包埋的块，在必要时应处理所有子宫颈以发现肿瘤。如果在子宫切除术材料中增加从子宫颈中采集的样本数量，并且如果可以在子宫内膜采样之前正确进行的阳性ECC之后进行锥切术，则诊断从肉眼看不到并且无法在临床上确定的肿瘤的可能性增加。

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