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Modality for Disseminated Intravascular Coagulation and Current Treatment

机译:弥散性血管内凝血和当前治疗方法

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Modality for Disseminated Intravascular Coagulation and Current Treatment yaren dirik sup1/sup, P?nar Kolusar? sup2/sup sup1/supVan Ozalp State Hospital, Department Of Internal Diseases, Van, Turkey sup2/supVan Education And Research Hospital, Department Of Anesthesiology And Reanimation, Van, Turkey Disseminated Intravascular Coagulation (DIC) is a systemic syndrome that causes thrombosis in small and medium-diameter vessels as a result of disruption of hemostatic balance by several reasons, and progresses with the consumption of thrombocyte and coagulation factors, severe hemorrhage and impaired organ perfusion as a result of activation of disseminated intravascular coagulation mechanism. DIC is always a complication that occurs together with some diseases and various secondary pathological conditions. The tissue factor which occurs as a result of tissue factor firstly activates the coagulation cascade; and overproduction of thrombin forms the basis of pathogenesis of DIC. The clinical course of DIC is generally under the influence of the underlying etiologic factor. There is not a laboratory test diagnosing DIC alone; however, the laboratory findings are indispensable for diagnosis. Treating the disease causing DIC and predominant signs of bleeding or thrombosis in clinical table, and conducting prophylaxis for preventing repetitions in chronic DIC cases are the main steps of treatment.
机译:弥散性血管内凝血和当前治疗的方式yaren dirik 1 ,P?nar Kolusar? 2 1 范·奥扎尔普州立医院,内脏科,土耳其,范 2 范教育与研究医院,麻醉科和复活科,范,土耳其弥散性血管内凝血(DIC)是一种全身综合征,由于多种原因导致止血平衡失调,导致中小直径血管中的血栓形成,并随着消耗血小板细胞和凝血因子,严重出血和器官受损而发展由于激活弥散性血管内弥散性凝血机制。 DIC总是与某些疾病和各种继发性病理状况一起发生的并发症。由组织因子引起的组织因子首先激活凝血级联;凝血酶的过量产生是DIC发病的基础。 DIC的临床过程通常受潜在病因的影响。没有单独诊断DIC的实验室测试。然而,实验室检查结果对于诊断是必不可少的。在临床表中治疗引起DIC和主要出血或血栓形成迹象的疾病,并进行预防以防止DIC慢性病例反复发作是主要治疗步骤。

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