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首页> 外文期刊>Iranian Journal of Neurology >The effect of body fat mass and fat free mass on migraine headache
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The effect of body fat mass and fat free mass on migraine headache

机译：体内脂肪量和无脂肪量对偏头痛的影响

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BackgroundObesity seems to be associated to migraine headache. Increase in body fat, especially in gluteofemoral region, elevates adiponectin and leptin secretion which in turn impair inflammatory processes that could be contributing to migraine risk. This study was designed to assess the relationship between body composition and risk of migraine for the first time.MethodsIn this cross-sectional study, 1510 middle-aged women who were visited in a weight reduction clinic of university were recruited. Migraine was diagnosed with HIS criteria. Body composition parameters including total fat mass (FATM), total fat free mass (FFM), truncal fat mass (TFATM), and truncal fat free mass (TFFM) was assessed using bioelectric impedance. We further assessed cardiovascular risk factors and smoking as confounding factors. To determine the real association between different variables and risk of migraine, the associations were adjusted by multivariate logistic regression analysis.ResultsElevation in fasting blood sugar, total cholesterol, LDL cholesterol, FFM, TFFM, and waist-to-hip ratio increased the risk of migraine. When the associations were adjusted for other factors, only the association between migraine and FFM remained statistically significant.ConclusionLower FFM increased the risk of migraine in overweight and obese individuals. In the other words, higher fat free mass could be a protective factor for migraine.
机译：背景肥胖症似乎与偏头痛有关。体内脂肪的增加，特别是在股骨腓骨区域，增加了脂联素和瘦素的分泌，继而损害了可能导致偏头痛风险的炎症过程。本研究旨在首次评估身体成分与偏头痛风险之间的关系。方法在本横断面研究中，招募了1510名在大学减肥诊所就诊的中年妇女。偏头痛被诊断为符合HIS标准。使用生物电阻抗评估包括总脂肪量（FATM），总无脂肪量（FFM），小腿脂肪量（TFATM）和小腿脂肪无量（TFFM）在内的身体成分参数。我们进一步评估了心血管危险因素和吸烟为混杂因素。为了确定不同变量与偏头痛风险之间的真实关联，通过多因素logistic回归分析对关联进行了调整。偏头痛。当对其他因素进行关联调整后，只有偏头痛与FFM之间的关联仍具有统计学意义。结论降低FFM会增加超重和肥胖个体的偏头痛风险。换句话说，较高的无脂肪量可能是偏头痛的保护因素。

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