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首页> 外文期刊>Iranian Journal of Microbiology >The antibacterial activity of methanolic Anacyclus pyrethrum and Pistacia lentiscus L. extract on Escherichia coli
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The antibacterial activity of methanolic Anacyclus pyrethrum and Pistacia lentiscus L. extract on Escherichia coli

机译：甲醇除虫菊酯和黄连木提取物对大肠杆菌的抗菌活性

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Background and Objectives: Antibiotic therapy is the main choice in treatment of Escherichia coli induced infections. Using herbal medication is an alternative choice in treatment of diseases. The aim of this study was to determine the antibacterial activity of two traditionally used herbs in Iranian medicine, Anacyclus pyrethrum and Pistacia lentiscus L., on Escherichia coli.Materials and Methods: The antibacterial effect of methanolic extract of Anacyclus pyrethrum and Pistacia lentiscus L. were examined in disk diffusion and skipped wells methods by measuring the diameter of inhibition zones around wells containing different concentrations of extracts from (10-1000 mg/ml) using standard broth macrodilution, method the MIC and MBC were defined.Results: The methanolic extract of Anacyclus pyrethrum from 300 to 1000 mg/ml and the methanolic extract of Pistacia lentiscus L. from 30 to 1000 mg/ml showed antibacterial activity on Escherichia coli. The MIC of Anacyclus pyrethrum and Pistacia lentiscus L. methanolic based extract were 800 and 1000 mg/ml, respectively. The MBC was achieved at 800 mg/ ml for methanolic extract of Anacyclus pyrethrum and Pistacia lentiscus L.Conclusion: The methanolic extract of Anacyclus pyrethrum and Pistacia lentiscus L. have antibacterial effect on Escherichia coli bacteria. This activity is dose-dependent.Keywords: Antibacterial activity, Anacyclus pyrethrum, Pistacia lentiscus L., Escherichia coli
机译：背景与目的：抗生素治疗是治疗大肠埃希菌引起的感染的主要选择。使用草药是治疗疾病的替代选择。这项研究的目的是确定伊朗传统的两种除草草药除虫菊除虫菊和黄连木P对大肠埃希菌的抗菌活性。材料与方法：除虫菊的甲醇提取物和黄连木P的甲醇提取物具有抗菌作用。采用圆盘扩散法和漏孔法通过使用标准肉汤大量稀释法测量含有不同浓度（10-1000 mg / ml）提取物的孔周围抑制区的直径来检查抑菌圈的直径，从而确定了MIC和MBC的方法。 300毫克/毫升至1000毫克/毫升的除虫菊除虫菊酯和30毫克/毫升至1000毫克/毫升的黄连木的甲醇提取物对大肠杆菌具有抗菌活性。菊苣除虫菊和甲醇黄连木提取物的MIC分别为800和1000 mg / ml。结论：拟除虫菊酯和Pistacia lentiscus L.的甲醇提取物对大肠杆菌具有800 mg / ml的MBC结论。该活性是剂量依赖性的。关键词：抗菌活性，除虫菊，无花果黄连木，大肠埃希菌

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