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首页> 外文期刊>ISRN Hypertension >Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
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Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline

机译：过渡到治疗慢性丙型肝炎病毒感染的高效疗法：政策声明和实施指南

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Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity and mortality disproportionately affect individuals born between 1945 and 1975. The recent development of well-tolerated and highly effective therapies for chronic HCV infection represents a unique opportunity to dramatically reduce rates of HCV-related complications and their costs. Critical to the introduction of such therapies will be well-designed provincial programming to ensure immediate treatment access to individuals at highest risk for complication, and well-defined strategies to address the global treatment needs of traditionally high-risk and marginalized populations. HCV practitioners in New Brunswick created a provincial strategy that stratifies treatment according to those at highest need, measures clinical impact, and creates evaluation strategies to demonstrate the significant direct and indirect cost savings anticipated with curative treatments.
机译：慢性丙型肝炎病毒（HCV）感染会增加全因死亡率，肝硬化，肝细胞癌，肝移植和整体医疗保健利用率。发病率和死亡率严重影响了1945年至1975年之间出生的人。慢性HCV感染耐受性强和有效疗法的最新发展为显着降低HCV相关并发症的发生率及其成本提供了独特的机会。引入此类疗法的关键在于精心设计的省级规划，以确保能够为面临最高并发症风险的个人立即获得治疗，以及制定明确的策略，以解决传统上高风险和边缘化人群的全球治疗需求。新不伦瑞克省的HCV从业人员制定了省级战略，根据最需要的人群对治疗进行分层，衡量临床影响，并制定评估策略，以证明预期通过治愈性治疗可节省的直接和间接费用。

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