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Biomarkers in Nonalcoholic Fatty Liver Disease

机译:非酒精性脂肪肝疾病中的生物标志物

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BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition characterized by insulin resistance, type 2 diabetes and fat accumulation in the liver that may cause hepatic inflammation and progressive scarring leading to nonalcoholic steatohepatitis (NASH) and irreversible liver damage (cirrhosis). As a result, there has been increased recognition of the need to assess and closely monitor individuals for risk factors of components of NAFLD and NASH, as well as the severity of these conditions using biomarkers.
机译:背景技术非酒精性脂肪肝疾病(NAFLD)是一种慢性肝脏疾病,其特征在于胰岛素抵抗,2型糖尿病和肝脏中的脂肪积聚,可能引起肝炎和进行性瘢痕形成,从而导致非酒精性脂肪性肝炎(NASH)和不可逆的肝损害(肝硬化)。结果,人们越来越认识到需要评估和密切监测个体的NAFLD和NASH成分的危险因素,以及使用生物标记物对这些疾病的严重性。

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