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首页> 外文期刊>Iranian red crescent medical journal >Comparison of Maternal Serum Magnesium Level in Pre-eclampsia and Normal Pregnant Women
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Comparison of Maternal Serum Magnesium Level in Pre-eclampsia and Normal Pregnant Women

机译：子痫前期与正常孕妇母体血清镁水平的比较

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Preeclampsia is a pregnancy multisystem disorder of unknown etiology. It is a significant cause of maternal and fetal morbidity and mortality. Objectives:: Due to the significant role of magnesium in physiological regulation of blood pressure, this study was conducted to measure the level of magnesium in pre-eclampsia and control groups since the beginning of the pregnancy. Materials and Methods:: We enrolled 500 pregnant women with gestational age of 18-22 weeks who had referred to the Section of Obstetrics and Gynecology of Hafez hospital of Shiraz. Initially, blood samples were obtained from all subjects. 26 cases with diagnosis of preeclampsia were detected at the next referral. For each case, two normal pregnant women, at the same gestational age, were considered as the control group. The second blood samples were obtained from all the cases and controls. All of the samples were sent to check the level of magnesium. The data was analyzed with the SPSS and Student’s t-test. Results:: The initial level of magnesium in pre-eclampsia women was not only significantly less than the control group (1.81 ± 0.25 mg/dl vs. 2.3 ± 0.44 mg/dl, P < 0.001), but also the secondary level was low, when the diagnosis was confirmed (1.72 ± 0.38 mg/dl vs. 2.2 ± 0.63 mg/dl, P < 0.05). Conclusions:: We found a gradual decrease in mean serum magnesium level with increasing period of gestation in the pre-eclampsia women. This implicates that the level of magnesium in preeclampsia was lower than the control group since the beginning of pregnancy. According to our results, checking the level of magnesium should be considered as the predicting factor of preeclampsia during the first evaluation of pregnancy.
机译：先兆子痫是一种病因不明的妊娠多系统疾病。它是母婴发病率和死亡率的重要原因。目的：由于镁在血压的生理调节中起着重要作用，因此该研究旨在测量妊娠开始以来子痫前期和对照组中镁的水平。材料和方法：：我们招募了500名胎龄为18-22周的孕妇，这些孕妇曾到设拉子的哈菲兹医院妇产科就诊。最初，从所有受试者获得血液样本。在下一次转诊时发现了26例先兆子痫的诊断病例​​。对于每种情况，将两个相同胎龄的正常孕妇作为对照组。从所有病例和对照中获得第二次血液样品。所有样品都送去检查镁含量。使用SPSS和学生t检验对数据进行了分析。结果：先兆子痫妇女的初始镁水平不仅显着低于对照组（1.81±0.25 mg / dl vs. 2.3±0.44 mg / dl，P <0.001），而且继发水平较低，当确定诊断时（1.72±0.38 mg / dl对2.2±0.63 mg / dl，P <0.05）。结论：我们发现子痫前期妇女的平均血清镁水平随着妊娠期的增加而逐渐降低。这暗示自怀孕开始以来子痫前期的镁水平低于对照组。根据我们的结果，在首次妊娠评估中，应将检查镁水平作为先兆子痫的预测因素。

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