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首页> 外文期刊>Iranian Journal of Reproductive Medicine >CONSERVATIVE MANAGEMENT IN YOUNG PATIENTS WITH BORDERLINE AND MALIGNANT OVARIAN TUMORS: OUTCOMES AND PREGNANCIES
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CONSERVATIVE MANAGEMENT IN YOUNG PATIENTS WITH BORDERLINE AND MALIGNANT OVARIAN TUMORS: OUTCOMES AND PREGNANCIES

机译：患有边界线和卵巢恶性肿瘤的年轻患者的保守治疗：结果和预后

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Background: Recent studies have showed conservative management in selective patients with borderline and malignant ovarian tumors is safe; therefore this management is considered in patients with ovarian tumor who desire to preserve fertility.Objective: This study has been performed to evaluate the clinical outcome and fertility in patients with ovarian tumors who were treated conservatively.Materials and Methods: All patients who were treated conservatively (preservation of uterus and at least one ovary) or were on follow-up and had recurrence were evaluated in Vali-e-Asr Hospital during 2000-2004.Results: Among 410 patients with ovarian tumors, 60 were treated conservatively. Age range was 13-34 years. Twenty-six of patients (43.3%) were desired pregnancy and 34 (56%) patients did not. Three (5%) patients had history of infertility. Histological types of tumors were as follows; 15(25%) borderline tumors, 10(16.7%) epithelial tumors, 26(43.3%) germ cell tumors, and 9(15%) sex cord tumors. Range follow-up time was 12-48 months. Seven term pregnancies in 6 patients had been occurred, 1 in epithelial group, 2 in germ cell group, 1 in sex cord group and 3 in borderline group. Nine patients had recurrence and 2 patients expired, including one patient with serous cyst carcinoma (Stage IIIC).This patient had refused radical surgery and referred to our center with recurrence. Another patient had immature teratoma (Stage IIIC).Conclusion: Conservative surgical management in young patients with stage I (grade 1, 2) of epithelial ovarian tumor and sex cord-stromal tumor and in patients with borderline and germ cell ovarian tumors could be performed in order to preserve fertility.
机译：背景：最近的研究表明，对于边缘性和恶性卵巢肿瘤的选择性患者，保守治疗是安全的。目的：本研究旨在评估经保守治疗的卵巢肿瘤患者的临床结局和生育能力。材料与方法：所有经保守治疗的患者在2000年至2004年间，对Vali-e-Asr医院（保留子宫和至少一个卵巢）或进行了随访并复发的患者进行了评估。结果：在410例卵巢肿瘤患者中，有60例接受了保守治疗。年龄范围是13-34岁。 26位患者（43.3％）希望怀孕，而34位（56％）不需要怀孕。三（5％）患者有不育史。肿瘤的组织学类型如下： 15（25％）交界性肿瘤，10（16.7％）上皮性肿瘤，26（43.3％）生殖细胞肿瘤和9（15％）性索肿瘤。范围随访时间为12-48个月。发生了7例足月妊娠6例，上皮组1例，生殖细胞组2例，性索组1例，交界组3例。 9例患者复发，2例患者死亡，其中1例患有浆液性囊癌（IIIC期），该患者拒绝接受根治性手术，并转诊至我中心。另一名患有畸胎瘤的患者（IIIC期）。结论：保守手术治疗于上皮性卵巢肿瘤和性索间质性肿瘤的I期（1、2级）的年轻患者以及交界性和生殖细胞性卵巢肿瘤的患者为了保持生育能力。

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