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首页> 外文期刊>Iranian Journal of Reproductive Medicine >EFFECTS OF VITAMIN E ON SPERM PARAMETERS AND REPRODUCTIVE HORMONES IN DEVELOPING RATS TREATED WITH PARA-NONYLPHENOL
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EFFECTS OF VITAMIN E ON SPERM PARAMETERS AND REPRODUCTIVE HORMONES IN DEVELOPING RATS TREATED WITH PARA-NONYLPHENOL

机译：维生素E对用偏壬基酚处理的发育中大鼠精子参数和生殖激素的影响

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Background: para-nonylphenol (p-NP) is able to induce malformations in male reproductive system.Objective: The aim of this study was to investigate the preventing role of vitamin E (Vit.E) on sperm parameters and reproductive hormones in developing rats.Materials and Methods: Pregnant rats were divided into 4 groups: control, p-NP, Vit.E and p-NP+Vit.E. Treatments were performed on day 7 of gestation and continued during weaning. The male pups were then divided into the same groups as the mothers and were treated till 90 days of age. Finally, body and left testis weight were recorded and left epididymis was cut in Hama€?s F10. Released sperm were used to analyze number, motility and viability of the sperm. Blood serum was used to assess follicle stimulating hormone (FSH), luteinizing hormone (LH), estrogen and testosterone.Results: In p-NP-treated rats, a significant decrease was found in body and testis weight, sperm number and sperm motility compared to control and p-NP+Vit.E groups. A significant increase was also found in sperm viability in Vit.E group (83.3
机译：背景：对壬基酚（p-NP）能够诱导雄性生殖系统畸形。目的：本研究旨在研究维生素E（Vit.E）对发育中大鼠精子参数和生殖激素的预防作用。材料与方法：孕鼠分为4组：对照组，p-NP，Vit.E和p-NP + Vit.E。在妊娠的第7天进行治疗，并在断奶期间继续治疗。然后将雄性幼崽与母亲分成相同的组，并治疗至90天大。最后，记录下哈马的F10的身体和左睾丸的重量，并切下左附睾。释放的精子用于分析精子的数量，运动性和生存力。血清用于评估卵泡刺激素（FSH），黄体生成素（LH），雌激素和睾丸激素。结果：在经p-NP处理的大鼠中，发现其体重和睾丸重量，精子数量和精子活力显着降低。来控制p-NP + Vit.E组。 Vit.E组的精子活力也显着增加（83.3）。

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