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首页> 外文期刊>Egyptian Journal of Medical Human Genetics >Magnesium, zinc and copper estimation in children with attention deficit hyperactivity disorder (ADHD)
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Magnesium, zinc and copper estimation in children with attention deficit hyperactivity disorder (ADHD)

机译:注意缺陷多动障碍(ADHD)儿童的镁,锌和铜估计

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Background Attention deficit hyperactivity disorder (ADHD) is a common neuro developmental disorder. Evidence for dietaryutritional treatments for (ADHD) varies widely, however recommended daily allowance of minerals and essential fatty acids is an ADHD-specific intervention. Aim of the work To estimate magnesium, zinc and copper levels in the sera and hair of children with ADHD and compare them to normal children and also to correlate these levels with the disease symptoms. Methods This case–control study was conducted on 20 patients with ADHD and 20 age and sex matched healthy controls. All subjects were subjected to psychiatric evaluation according to DSMIV-R, magnesium, zinc and copper estimation in serum and hair follicles. ADHD children were further assessed by the Stanford Binnet intelligence scale for children, Conners’ parent rating scale, and Wisconsin’s card sorting test. Results Magnesium, zinc and copper deficiencies were found in 13 (65%), 14 (60%) and 12 (70%) of ADHD children respectively. Magnesium and zinc deficiencies were found to be correlated with hyperactivity, inattention and impulsivity. However, this correlation was not found in the copper deficient ADHD cases. Conclusion Children with ADHD have lower levels of zinc, copper and magnesium compared to both laboratory reference ranges and to normal controls in both hair and serum. These deficiencies are correlated with the core symptoms of ADHD.
机译:背景技术注意缺陷多动障碍(ADHD)是一种常见的神经发育障碍。饮食/营养治疗(ADHD)的证据差异很大,但是建议每日摄入矿物质和必需脂肪酸是ADHD特有的干预措施。工作目的评估多动症儿童血清和头发中的镁,锌和铜含量,并将其与正常儿童进行比较,并将这些含量与疾病症状相关联。方法这项病例对照研究针对20例多动症患者和20名年龄和性别相匹配的健康对照者进行。根据DSMIV-R,血清和毛囊中镁,锌和铜的估计,对所有受试者进行精神病学评估。斯坦福·宾纳儿童智力量表,康纳斯的父母评分量表和威斯康星州的卡片分类测试对ADHD儿童进行了进一步评估。结果在多动症儿童中分别发现13、65(65%),14(60%)和12(70%)的镁,锌和铜缺乏。发现镁和锌缺乏与多动,注意力不集中和冲动有关。但是,在铜缺乏的多动症病例中未发现这种相关性。结论与实验室参考范围和正常对照相比,ADHD儿童的头发和血清中锌,铜和镁含量较低。这些缺陷与多动症的核心症状有关。

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