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首页> 外文期刊>Egyptian Journal of Medical Human Genetics >Comparative frequency and allelic distribution of ABO and Rh (D) blood groups of major tribal communities of southern Bangladesh with general population and their determinants
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Comparative frequency and allelic distribution of ABO and Rh (D) blood groups of major tribal communities of southern Bangladesh with general population and their determinants

机译：孟加拉国南部主要部落社区的ABO和Rh（D）血型与一般人群及其决定因素的比较频率和等位基因分布

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Background Allelic distribution of major blood groups (ABO and rhesus) has not been defined in Bangladeshi population. Determinants of blood group frequency in this region have not been studied properly. Aim To determine ABO and rhesus blood group frequency and allelic distribution in a multiethnic area of Bangladesh and to explore possible genetic, racial and environmental factors influence as determinants of major blood groups. Subjects and methods Data collected retrospectively from blood group register of Rangamati General Hospital (2006–2011). Four tribal (Chakma, Marma, Tanchangya and Tripura) and general Bengali population were included in the study. Results Collectively all tribal had distinct ABO phenotypic frequency (B>A>O>AB) which is different from Bengali population (O>B>A>AB). Tripura’s showed a unique pattern of A>B>AB>O. Overall tribal had higher frequency of B and AB group ( P B>A in all study groups except Tripura (A>O>B). Rhesus negative group was very uncommon in study groups. Data among tribal suggest their common origin as well as drift from original population due to possible founder effect among Tripura’s. Despite being malaria endemic zone the protective group O was less ( P <0.0001) among native tribal (23%) and high among migrating Bengali (34%).
机译：背景在孟加拉国人群中，主要血型（ABO和恒河猴）的等位基因分布尚未确定。该区域血型频率的决定因素尚未得到适当研究。目的确定孟加拉国多民族地区的ABO和恒河猴血型频率及等位基因分布，并探讨可能的遗传，种族和环境因素对主要血型的决定因素的影响。对象和方法回顾性研究从Rangamati总医院血型登记簿中收集的数据（2006-2011年）。这项研究包括四个部落（查克马，马尔马，坦昌亚和特里普拉）和孟加拉总人口。结果总的来说，所有部落的ABO表型频率（B> A> O> AB）均不同于孟加拉族（O> B> A> AB）。 Tripura的显示方式是A> B> AB> O。总体而言，部落和人群中B和AB组的发生率较高（除Tripura以外，所有研究组中PB> A（A> O> B），恒河猴阴性组在研究组中很少见，部落之间的数据表明它们的共同起源和漂移由于在Tripura族群中可能有创始者的影响，原始种群的保护群体O虽然是疟疾流行区，但土著部落中的保护基O较少（P <0.0001）（23％），而在孟加拉国迁徙者中的保护基团O高（34％）。

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