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首页> 外文期刊>EFSA Journal >Evaluation of di‐calcium malate, used as a novel food ingredient and as a source of calcium in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes
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Evaluation of di‐calcium malate, used as a novel food ingredient and as a source of calcium in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes

机译：苹果酸二钙的评估，苹果酸二钙被用作普通食品，食品补充剂，用于控制体重的总饮食替代品和用于特殊医疗目的的食品中的新型食品成分和钙来源

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The present scientific opinion deals with the evaluation of the safety of di‐calcium malate (DCM) proposed as a novel food ingredient and as a source of calcium for use in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes (FSMP), and with the bioavailability of calcium from this source. The structural formula of the proposed complex is based on expert judgement and not supported by any analytical data. On the basis of the available data, the Panel concluded that there was insufficient scientific evidence of a difference between the proposed novel food ingredient named as di‐calcium malate (DCM) and calcium malate already authorised as a source of calcium included in Annex II to Directive 2002/46/EC. Accordingly, the Panel was unable to assess the safety of DCM as a novel food ingredient. On the basis of the results provided, the Panel considered that DCM does not completely dissociate into calcium and malic acid. The Panel concluded that when DCM dissociates, calcium would be available following ingestion of DCM and the bioavailability would appear similar to values reported for other sources of calcium already permitted. Furthermore, the Panel concluded that on the basis of the information available it was not possible to calculate the exposure to DCM as a source of calcium to foods for the general population, food supplements, total diet replacement for weight control and FSMP.
机译：本科学意见涉及对苹果酸二钙（DCM）的安全性的评估，该酸被提议作为一种新型食品成分和作为普通人群食品，食物补充剂，总饮食替代品以控制体重的钙源。特殊医疗用途（FSMP）的食品，以及这种来源的钙的生物利用度。拟建综合体的结构公式基于专家判断，没有任何分析数据支持。根据现有数据，小组得出结论认为，没有足够的科学证据证明拟议的新型食品成分苹果酸二钙与已经被批准为食品添加剂法附件二中所列钙源的苹果酸钙之间存在差异。指令2002/46 / EC。因此，小组无法评估DCM作为新型食品成分的安全性。根据提供的结果，小组认为DCM不会完全分解为钙和苹果酸。专家小组得出结论，当DCM解离时，摄入DCM后即可得到钙，其生物利​​用度似乎与已报告的其他钙来源的报道值相似。此外，小组得出结论，根据现有信息，无法计算出DCM作为普通人群食物，食物补充剂，控制体重的总饮食替代品和FSMP中钙来源的DCM暴露量。

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