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首页> 外文期刊>Einstein (So Paulo) >Fecal microbiota transplant by push enteroscopy to treat diarrhea caused by Clostridium difficile
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Fecal microbiota transplant by push enteroscopy to treat diarrhea caused by Clostridium difficile

机译：推入式肠镜粪便菌群移植治疗艰难梭菌引起的腹泻

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ABSTRACT Clostridium difficile is the major etiological agent of pseudomembranous colitis and is found in up to 20% of adult inpatients. The recommended treatment is antibiotic therapy with metronidazole and/or vancomycin. However, the recurrence rate may reach up to 25% and it increases in each episode. The newest alternative to treat diarrhea due to recurrent Clostridium difficile is fecal microbiota transplantation. The procedure was performed in 12 patients, with a 6-month follow-up on 10 of them. Of the ten cases, bacterial recurrence was diagnosed in only one patient, after a course of antibiotic to treat urinary tract infection, without presenting with diarrhea. The particularity of our study, besides being an unprecedented event in South America, is the way to perform the infusion of fecal microbiota by enteroscopy.
机译：摘要艰难梭菌是假膜性结肠炎的主要病因，在成年住院患者中高达20％被发现。推荐的治疗方法是用甲硝唑和/或万古霉素进行抗生素治疗。但是，复发率可能高达25％，并且每次发作都会增加。治疗复发性艰难梭菌引起的腹泻的最新替代方法是粪便微生物群移植。该程序在12例患者中进行，其中10例接受了6个月的随访。在十例病例中，仅用一例抗生素治疗了尿路感染，却没有出现腹泻，但只有一名患者被诊断出细菌复发。除了在南美发生的史无前例的事件之外，我们研究的特殊性是通过肠镜检查进行粪便微生物群输注的方式。

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