Outpatient treatment of sleep disorders in Alzheimer patients

Einstein Francisco Camargos; Francisca Magalh?es Scoralick; Marco Polo Dias Freitas; Otávio Toledo Nóbrega

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Outpatient treatment of sleep disorders in Alzheimer patients

机译：门诊老年痴呆症患者的睡眠障碍

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Sleep disorders are common in patients with Alzheimer dementia and affect the quality of life of patients and of their caregivers. Despite the rising number of studies in the area, almost all of them are about non-pharmacological treatment. Our objective was to review the literature concerning pharmacological and non-pharmacological approaches to treat sleep disorders of elderly patients with Alzheimer dementia in the ambulatory setting. The treatments revised consisted of sleep hygiene and/or use of intense light coupled or not with use of melatonin, cholinesterase inhibitors, antipsychotics, hypnotics or antidepressants. In addition to the non-pharmacological measures, there is evidence that the use of trazodone may aid the treatment of sleep disorders of older individuals with Alzheimer dementia. More studies are necessary to examine the non-pharmacological and pharmacological treatments revised herein.

机译：睡眠障碍在阿尔茨海默氏痴呆患者中很常见，并且会影响患者及其护理人员的生活质量。尽管该地区的研究数量在增加，但几乎所有研究都是关于非药物治疗的。我们的目的是回顾有关在非卧床环境下治疗老年痴呆症老年患者睡眠障碍的药理和非药理方法的文献。修改后的治疗包括睡眠卫生和/或使用强光或不使用褪黑激素，胆碱酯酶抑制剂，抗精神病药，催眠药或抗抑郁药。除非药理学措施外，有证据表明使用曲唑酮可能有助于治疗老年痴呆症患者的睡眠障碍。为了研究本文修订的非药理学和药理学方法，需要进行更多的研究。

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《Einstein (So Paulo)》 |2015年第3期|共5页
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Einstein Francisco Camargos; Francisca Magalh?es Scoralick; Marco Polo Dias Freitas; Otávio Toledo Nóbrega;
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中图分类预防医学、卫生学;
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2. Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015 [J] . Auger R. Robert, Burgess Helen J., Emens Jonathan S., Journal of clinical sleep medicine: JCSM : official publication of the American Academy of Sleep Medicine . 2015,第10期

机译：治疗内在昼夜节律性睡眠-觉醒障碍的临床实践指南：晚期睡眠-觉醒相位障碍（ASWPD），延迟性睡眠-觉醒相位障碍（DSWPD），非24小时睡眠-觉醒节奏障碍（N24SWD）和不规则的睡眠-苏醒节律障碍（ISWRD）。 2015年更新
3. The effect of sleep-disordered breathing on stages of sleep in patients with Alzheimer's disease. [J] . Cooke JR, Liu L, Natarajan L, Behavioral sleep medicine . 2006,第4期

机译：睡眠呼吸障碍对阿尔茨海默氏病患者的睡眠阶段的影响。
4. A 0.21 μJ patient-specific REM/Non-REM sleep classifier for Alzheimer patients [C] . Muhammad Awais Bin Altaf, Wala Saadeh IEEE biomedical circuits and systems conference . 2017

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5. Intensive Outpatient Treatment Program for Patients with Depressive Disorder: A Parental Perspective [D] . Akpan, Emmanuel. 2018

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6. Outpatient treatment of sleep disorders in Alzheimer patients [O] . Francisca Magalhães Scoralick, Einstein Francisco Camargos, Marco Polo Dias Freitas, 2015

机译：门诊老年痴呆症患者的睡眠障碍
7. Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015 [O] . R. Robert Auger, Helen J. Burgess, Jonathan S. Emens, 2015

机译：治疗内在昼夜节律睡眠障碍的临床实践指南：先进的睡眠唤醒期疾病（ASWPD），延迟睡眠术后疾病（DSWPD），非24小时睡眠节奏障碍（N24WD），以及不规则的睡眠唤醒节奏障碍（ISWRD）。 2015年的更新

Outpatient treatment of sleep disorders in Alzheimer patients

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