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Effects of overnight fasting on handgrip strength in inpatients

机译：过夜空腹对住院病人握力的影响

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Objective: To investigate the effects of overnight fasting on handgrip strength of adult inpatients. Methods: A prospective clinical study enrolling 221 adult patients. The endpoints were handgrip strength obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative handgrip strength (mean of handgrip strength after breakfast and lunch) in the same day. The mean of three handgrip strength measures was considered to represent each time point. A cut-off for the mean overnight fasting handgrip strength at the 50 th percentile (35.5kg for males and 27.7kg for females) was used for comparisons. We registered the age, sex, current and usual weight (kg), weight loss (kg), diagnosis of cancer, nutritional status, elderly frequency, digestive tract symptoms, type of oral diet, and the amount of dinner ingested the night before handgrip strength (zero intake, until 50%, 100% and 100%). Results: Handgrip strength evaluated after an overnight fasting (31.2±8.7kg) was lesser when compared with handgrip strength after breakfast (31.6±8.8kg; p=0.01), and with cumulative handgrip strength (31.7±8.8kg; p0.001). Handgrip strength was greater in patients who ingested 100% (33.2±9.1kg versus 30.4±8.4kg; p=0.03) and above 50% of dinner (32.1±8.4kg versus 28.6±8.8kg; p=0.006). Multivariate analysis showed that ingesting below 50% of dinner, severe malnutrition, and elderly were independent factors for handgrip strength reduction after overnight fasting. Conclusion: The muscular function was impaired after an overnight fasting of adult patients hospitalized for medical treatment, especially for those with low ingestion, malnourished and elderly.
机译：目的：探讨过夜空腹对成年住院病人握力的影响。方法：前瞻性临床研究招募了221名成年患者。终点为通过测力计在三个时间点（隔夜空腹，早餐后和午餐后的早晨）获得的握力，以及同一天的累积握力（早餐和午餐后的握力平均值）。认为三个握力强度度量的平均值代表每个时间点。比较时使用的平均过夜空腹握力强度的临界值在第50个百分点（男性为35.5kg，女性为27.7kg）。我们记录了年龄，性别，当前和通常的体重（kg），体重减轻（kg），癌症的诊断，营养状况，老年人的频率，消化道症状，口服饮食的类型以及握紧前一天晚上的晚餐摄入量力量（零摄入，直到50％，<100％和100％）。结果：与早餐后的握力（31.6±8.8kg; p = 0.01）相比，过夜禁食后的握力（31.2±8.7kg）要小，累积握力（31.7±8.8kg; p <0.001）要小。 。进食100％（33.2±9.1kg vs 30.4±8.4kg; p = 0.03）和餐后50％以上的患者（32.1±8.4kg vs 28.6±8.8kg; p = 0.006），握力更高。多因素分析表明，进食不足50％的晚餐，严重的营养不良和老年人是禁食过夜后握力下降的独立因素。结论：入院就诊的成年患者过夜禁食后肌肉功能受损，特别是对于那些低摄入，营养不良和老年人的患者。

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