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Not all that shines is cancer: pulmonary cryptococcosis mimicking lymphoma in [(18)] F fluoro-2-deoxy-D-glucose positron emission tomography

机译:并非所有的癌症都闪闪发光:在[(18)] F氟-2-脱氧-D-葡萄糖正电子发射断层扫描中模拟淋巴瘤的肺隐球菌病

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We report of a case of pulmonary cryptococcosis mimicking lymphoma in a positron emission tomography (FDG-PET) scan. A 62-year old man with diffuse large B-cell lymphoma had complete resolution of abdominal and pulmonary lesions after three cycles of rituximab-based chemotherapy (R-CHOP). However, FDG-PET showed new pulmonary nodules, suggesting active lymphoma. Chronic inflammatory granuloma was seen in the histopathological exam, with round-shaped structures compatible with fungus, later identified as Cryptococcus neoformans on culture. The lesions disappeared after 6 weeks of fluconazole therapy, and the patient could continue chemotherapy without further infectious complications.
机译:我们在正电子发射断层扫描(FDG-PET)扫描中报告了一个模仿淋巴瘤的肺隐球菌病病例。一名62岁的弥漫性大B细胞淋巴瘤患者在接受了三轮基于利妥昔单抗的化疗(R-CHOP)后,腹部和肺部病变得到了完全缓解。但是,FDG-PET显示出新的肺结节,提示活动性淋巴瘤。在组织病理学检查中发现了慢性炎性肉芽肿,其圆形结构与真菌相容,后来在培养物中被鉴定为新隐球菌。氟康唑治疗6周后病灶消失,患者可以继续化疗而无进一步的感染并发症。

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