• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Emerging themes in epidemiology >Application of loop analysis for the qualitative assessment of surveillance and control in veterinary epidemiology
【24h】

Application of loop analysis for the qualitative assessment of surveillance and control in veterinary epidemiology

机译：循环分析在兽医流行病学监测与控制定性评估中的应用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Systems for animal disease mitigation involve both surveillance activities and interventions to control the disease. They are complex organizations that are described by partial or imprecise data, making it difficult to evaluate them or make decisions to improve them. A mathematical method, called loop analysis, can be used to model qualitatively the structure and the behavior of dynamic systems; it relies on the study of the sign of the interactions between the components of the system. This method, currently widely used by ecologists, has to our knowledge never been applied in the context of animal disease mitigation systems. The objective of the study was to assess whether loop analysis could be applied to this new context. We first developed a generic model that restricted the applicability of the method to event-based surveillance systems of endemic diseases, excluding the emergence and eradication phases. Then we chose the mitigation system of highly pathogenic avian influenza (HPAI) H5N1 in Cambodia as an example of such system to study the application of loop analysis to a real disease mitigation system. Results Breaking down the generic model, we constructed a 6-variables model to represent the HPAI H5N1 mitigation system in Cambodia. This construction work improved our understanding of this system, highlighting the link between surveillance and control which is unclear in traditional representations of this system. Then we analyzed the effect of the perturbations to this HPAI H5N1 mitigation system that we interpreted in terms of investment in a given compartment. This study suggested that increasing intervention at a local level can optimize the system’s efficiency. Indeed, this perturbation both decreases surveillance and intervention costs and reduces the disease’s occurrence. Conclusion Loop analysis can be applied to disease mitigation systems. Its main strength is that it is easy to design, focusing on the signs of the interactions. It is a simple and flexible tool that could be used as a precursor to large-scale quantitative studies, to support reflection about disease mitigation systems structure and functioning.
机译：背景技术用于减轻动物疾病的系统涉及监视活动和控制疾病的干预措施。它们是由部分或不精确的数据描述的复杂组织，因此很难对其进行评估或做出决定来改进它们。一种称为循环分析的数学方法可以用来定性地建模动态系统的结构和行为。它依赖于对系统组件之间交互作用的符号的研究。据我们所知，这种方法目前已被生态学家广泛使用，从未应用于减轻动物疾病的系统中。该研究的目的是评估循环分析是否可以应用于这种新环境。我们首先开发了一个通用模型，该模型将方法的适用性限制在流行病的基于事件的监视系统中，不包括出现和消除阶段。然后，我们以柬埔寨的高致病性禽流感（HPAI）H5N1缓解系统为例，研究了环路分析在实际疾病缓解系统中的应用。结果分解通用模型，我们构建了一个6变量模型来代表柬埔寨的HPAI H5N1缓解系统。这项构建工作改善了我们对该系统的理解，突出了监视和控制之间的联系，而在该系统的传统表示形式中尚不清楚。然后，我们分析了扰动对此HPAI H5N1缓解系统的影响，我们根据对特定隔间的投资来解释该影响。这项研究表明，在地方一级增加干预可以优化系统的效率。实际上，这种干扰既降低了监视和干预成本，又减少了疾病的发生。结论循环分析可应用于疾病缓解系统。它的主要优点是易于设计，着重于交互的迹象。它是一种简单而灵活的工具，可以用作大规模定量研究的前身，以支持对疾病缓解系统结构和功能的反思。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号