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Vulnerability of Brazilian municipalities to hantavirus infections based on multi-criteria decision analysis

机译:基于多标准决策分析的巴西市政当局对汉坦病毒感染的脆弱性

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Background Hantavirus infection is an emerging zoonosis transmitted by wild rodents. In Brazil, high case-fatality rates among humans infected with hantavirus are of serious concern to public health authorities. Appropriate preventive measures partly depend on reliable knowledge about the geographical distribution of this disease. Methods Incidence of hantavirus infections in Brazil (1993–2013) was analyzed. Epidemiological, socioeconomic, and demographic indicators were also used to classify cities’ vulnerability to disease by means of multi-criteria decision analysis (MCDA). Results From 1993 to 2013, 1752 cases of hantavirus were registered in 16 Brazilian states. The highest incidence of hantavirus was observed in the states of Mato Grosso (0.57/100,000) and Santa Catarina (0.13/100,000). Based on MCDA analysis, municipalities in the southern, southeastern, and midwestern regions of Brazil can be classified as highly vulnerable. Most municipalities in northern and northeastern Brazil were classified as having low vulnerability to hantavirus cardiopulmonary syndrome. Conclusions Although most human infections by hantavirus registered in Brazil occurred in the southern region of the country, a greater vulnerability to hantavirus was found in the Brazilian Midwest. This result reflects the need to strengthen surveillance where the disease has thus far gone unreported.
机译:背景汉坦病毒感染是由野生啮齿动物传播的一种新兴的人畜共患病。在巴西,汉坦病毒感染者中的高致死率是公共卫生当局严重关注的问题。适当的预防措施部分取决于对这种疾病地理分布的可靠了解。方法分析巴西(1993-2013年)汉坦病毒感染的发生率。流行病学,社会经济和人口统计指标还被用于通过多标准决策分析(MCDA)对城市的疾病易感性进行分类。结果从1993年到2013年,巴西16个州注册了1752例汉坦病毒。在马托格罗索州(0.57 / 100,000)和圣卡塔琳娜州(0.13 / 100,000)州,汉坦病毒的发病率最高。根据MCDA分析,可以将巴西南部,东南部和中西部地区的城市划分为高度脆弱的地区。巴西北部和东北部的大多数城市被归类为对汉坦病毒性心肺综合征的脆弱性较低。结论尽管在巴西登记的汉坦病毒大多数人类感染发生在该国南部地区,但在巴西中西部发现了更易感染汉坦病毒的情况。该结果表明,需要加强对迄今尚未报告的疾病的监测。

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