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首页> 外文期刊>Endocrinology, Diabetes & Metabolism >The new FreeStyle libre flash glucose monitoring system improves the glycaemic control in a cohort of people with type 1 diabetes followed in real‐life conditions over a period of one year
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The new FreeStyle libre flash glucose monitoring system improves the glycaemic control in a cohort of people with type 1 diabetes followed in real‐life conditions over a period of one year

机译：新型FreeStyle libre闪速血糖监测系统可改善在现实生活中在一年内随访的一组1型糖尿病患者的血糖控制

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Aims Using the novel FreeStyle Libre (FSL), glucose monitoring (FGM) system becomes increasingly popular among people with type 1 diabetes (T1D) and is associated with less and shorter hypoglycaemic events without deterioration of HbA1c. There are not yet data reporting the impact of FGM in people with T1D in real‐life conditions. We sought of evaluating the tolerance, the acceptance and the efficacy of the FGM system in routine medical practice. Methods This 12‐month observational study included 120 individuals with T1D evaluated every 3 months. After having been instructed about FGM utilization, participants were trained to optimize the glycaemic control. Results Participants stopped immediately of measuring capillary blood glucose (2.88 ± 0.12 per day) (mean ± SEM) after having received the first FSL device and the number of scans per day increased up to 8.87 ± 0.58 per day. HbA1c levels decreased from 8.51% ± 0.14% at baseline to 7.77% ± 0.09% after 3 months to slightly increase to 7.92% ± 0.09% at 12 months, in correlation with the number of scans per day. The number (but not the duration) of hypoglycaemic events slightly increased from 16.9 ± 1.44 per month at baseline to 24.0 ± 2.91 per month at 12 months, after reaching a peak of 26.4 ± 2.31 per month at 6 months. They were correlated with improved HbA1c. Conclusion Our study shows that using the FGM system improves HbA1c levels in people with T1D along with a moderate increase in the number of mild hypoglycaemic events. The new FGM system facilitates the therapeutic empowerment of people with T1D, but in a context of structured education.
机译：目的使用新颖的FreeStyle Libre（FSL），葡萄糖监测（FGM）系统在1型糖尿病（T1D）患者中变得越来越普遍，并且与越来越少的降血糖事件相关，而不会导致HbA1c恶化。尚无数据报道在现实生活中FGM对T1D患者的影响。我们试图评估FGM系统在常规医学实践中的耐受性，可接受性和有效性。方法这项为期12个月的观察性研究包括每3个月评估120例T1D患者。在被告知有关FGM的使用后，对参与者进行培训以优化血糖控制。结果参加者在收到第一台FSL设备后立即停止测量毛细血管血糖（每天2.88±0.12）（平均值±SEM），并且每天的扫描次数增加到每天8.87±0.58。 HbA1c水平从基线时的8.51％±0.14％降至3个月后的7.77％±0.09％，在12个月时略增至7.92％±0.09％，这与每天的扫描次数相关。在6个月达到每月26.4±2.31的峰值后，降血糖事件的数量（但不是持续时间）从基线的每月16.9±1.44略增至12个月的每月24.0±2.91。它们与改善的HbA1c相关。结论我们的研究表明，使用FGM系统可以改善T1D患者的HbA1c水平，同时轻度降血糖事件的数量也适度增加。新的FGM系统可促进T1D患者的治疗能力，但要有系统的教育。

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