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首页> 外文期刊>Endocrine journal >Final Height of Japanese Patients with X-Linked Hypophosphatemic Rickets
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Final Height of Japanese Patients with X-Linked Hypophosphatemic Rickets

机译：X连锁低磷酸盐血症cket病的日本患者的最终身高

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References(15) Cited-By(3) X-linked hypophosphatemic rickets (XLH) is one of the most common causes of rickets in infancy and childhood. Combination therapy of vitamin D and phosphate is generally used for patients with XLH. Effect of treatment of vitamin D and phosphate during childhood on final height of XLH has to be elucidated in Japanese. There have been only three Caucasian studies on final height of XLH with treatment since childhood. Purpose of this study is to report adult height and therapeutic effect of 22 Japanese participants (5 males, 17 females) with XLH who were treated with phosphate (33-200mg/kg/day as phosphorus divided into 3 or 4 doses) and vitamin D (vitamin D2 or 1α-hydroxyvitamin D3) for more than five years and evaluate effect of the treatment on the final height retrospectively. Final height (FHt) for all participants was -1.69±1.11 SD. FHt (-1.69±1.11 SD) was significantly higher than height at the initiation of treatment (-2.38±0.88 SD) for all participants (P0.01). In conclusion, combination therapy of vitamin D and phosphate improved final height of Japanese patients with XLH as is similar to previous Caucasian studies.
机译：参考文献（15）被引用的By（3）X连锁低磷酸盐血症性rick病（XLH）是婴儿期和儿童期病的最常见原因之一。 XLH患者通常使用维生素D和磷酸盐的联合疗法。必须用日语阐明儿童时期维生素D和磷酸盐的治疗对XLH最终身高的影响。从儿童期开始，只有三项关于XLH最终身高的白种人研究。这项研究的目的是报告22例接受磷酸盐（33-200mg / kg /天，磷分为3或4剂）和维生素D治疗的XLH的日本参与者（5例男性，17例女性）的成年身高和疗效。 （维生素D2或1α-羟基维生素D3）服用五年以上，并回顾性评估治疗对最终身高的影响。所有参与者的最终身高（FHt）为-1.69±1.11 SD。对于所有参与者，FHt（-1.69±1.11 SD）显着高于治疗开始时的身高（-2.38±0.88 SD）（P <0.01）。总之，与以前的白种人研究相似，维生素D和磷酸盐的联合治疗可改善日本XLH患者的最终身高。

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