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首页> 外文期刊>Irish Veterinary Journal >Aspects of bovine herpesvirus 1 and bovine viral diarrhoea virus herd-level seroprevalence and vaccination in dairy and beef herds in Northern Ireland
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Aspects of bovine herpesvirus 1 and bovine viral diarrhoea virus herd-level seroprevalence and vaccination in dairy and beef herds in Northern Ireland

机译:北爱尔兰奶牛和牛群中牛疱疹病毒1和牛病毒性腹泻病毒群的血清阳性率和疫苗接种情况

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摘要

Background Infections with bovine herpesvirus 1 (BoHV-1) and bovine viral diarrhoea (BVD) virus cause diseases of cattle with a worldwide distribution. The primary objective of the present study was to describe aspects of herd-level BoHV-1 and BVDV seroprevalence (based on testing of pooled sera) and control on farms in Northern Ireland, including vaccine usage. An indirect antibody ELISA test (SVANOVA, Biotech AB, Uppsala, Sweden) was applied to serum pools which were constructed from serum samples taken for a cross-sectional study of a convenience sample of 500 Northern Irish dairy and beef cow herds in 2010, for which vaccination status was determined by telephone survey. The herd-level seroprevalence of BoHV-1 and BVDV in Northern Ireland was estimated in non-vaccinating herds and associations between possible risk factors (herd type and herd size (quartiles)) and herd-level prevalence were determined using chi-squared analysis. Results The herd-level seroprevalence (of BoHV-1 and BVDV) in non-vaccinating herds was 77.3% (95% CI: 73.6–80.9%) and 98.4% (95% CI: 97.3–99.5%) respectively in the cross-sectional study. A significant difference existed in BoHV-1 herd-level seroprevalence between dairy and beef herds (74.7% vs 86.5% respectively; p??0.91). A significant association was found between herd size (quartiles) and herd-level classification for BoHV-1 herd-level seroprevalence based on cut-off percentage positivity (COPP) (p? 15.5% and 23.8% of farmers used BoHV-1 and BVDV vaccines, respectively. BoHV-1 vaccine was used in 30% of dairy herds and in 11% of beef herds, while BVDV vaccine was used in 46% and 16% of dairy and beef herds, respectively. Conclusions The results from this study indicate that the true herd-level seroprevalences to bovine herpesvirus 1 and bovine virus diarrhoea virus in non-vaccinating herds in Northern Northern Ireland are 77.3% (95% CI: 73.6–80.9%) and 98.4% (95% CI: 97.3–99.5%), respectively. The present study will assist in guiding regional policy development and establish a baseline against which the progress of current and future control and eradication programmes can be measured.
机译:背景牛疱疹病毒1(BoHV-1)和牛病毒性腹泻(BVD)病毒的感染引起了全世界范围内的牛疾病。本研究的主要目的是描述北爱尔兰的牛群水平BoHV-1和BVDV血清阳性率(基于合并血清的测试)和控制,包括疫苗的使用。间接抗体酶联免疫吸附试验(SVANOVA,Biotech AB,乌普萨拉,瑞典)应用于血清库,血清库由血清样品构成,用于在2010年对500个北爱尔兰奶牛和肉牛种群的方便性样品进行横断面研究,通过电话调查确定了哪种疫苗接种状态。在非疫苗接种的牛群中估计了BoHV-1和BVDV的牛群血清阳性率,并使用卡方分析确定了可能的危险因素(牛群类型和牛群大小(四分位数))与牛群水平患病率之间的关联。结果在非接种牛群中,BoHV-1和BVDV的牛群血清阳性率分别为77.3%(95%CI:73.6–80.9%)和98.4%(95%CI:97.3–99.5%)。截面研究。乳牛和牛肉群之间BoHV-1群血清阳性率存在显着差异(分别为74.7%和86.5%; p ?? 0.91)。根据截断百分比阳性率(COPP),发现BoHV-1牛群血清阳性率的牛群大小(四分位数)与牛群等级之间存在显着关联(p。15.5%和23.8%的农民使用BoHV-1和BVDV这项研究的结果表明,BoHV-1疫苗分别用于30%的奶牛场和11%的牛群,而BVDV疫苗分别用于46%和16%的奶牛场和牛群。在北爱尔兰北部未接种疫苗的牛群中,牛疱疹病毒1和牛病毒性腹泻病毒的真实牛群血清阳性率分别为77.3%(95%CI:73.6–80.9%)和98.4%(95%CI:97.3–99.5%)本研究将有助于指导区域政策的发展,并建立一个基线,以此为基础可以衡量当前和未来的控制与根除计划的进展。

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