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Discharge hemoglobin and outcome in patients with acute nonvariceal upper gastrointestinal bleeding

机译:急性非静脉曲张性上消化道出血患者的血红蛋白释放及预后

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Background and study aims: Many patients with acute gastrointestinal bleeding present with anemia and frequently require red blood cell (RBC) transfusion. A restrictive transfusion strategy and a low hemoglobin (Hb) threshold for transfusion had been shown to produce acceptable outcomes in patients with acute upper gastrointestinal bleeding. However, most patients are discharged with mild anemia owing to the restricted volume of packed RBCs (pRBCs). We investigated whether discharge Hb influences the outcome in patients with acute nonvariceal upper gastrointestinal bleeding. Patients and methods: We retrospectively analyzed patients with upper gastrointestinal bleeding who had received pRBCs during hospitalization between January 2012 and January 2014. Patients with variceal bleeding, malignant lesion, stroke, or cardiovascular disease were excluded. We divided the patients into 2 groups, low (8?g/dL?≤?Hb 10?g/dL. Patients in the low Hb group had a lower consumption of pRBCs and shorter hospital stay than did those in the high Hb group.?The Hb levels were not fully recovered at outpatient follow-up until 7 days after discharge; however, most patients showed Hb recovery at 45 days after discharge. The rate of rebleeding after discharge was not significantly different between the 2 groups. Conclusions: In patients with acute upper gastrointestinal bleeding, a discharge Hb between 8 and 10?g/dL was linked to favorable outcomes on outpatient follow-up.?Most patients recovered from anemia without any critical complication within 45 days after discharge.
机译:背景和研究目的:许多患有急性胃肠道出血的患者出现贫血,并经常需要输注红细胞(RBC)。在急性上消化道出血的患者中,限制性输血策略和低血红蛋白(Hb)阈值已显示出可接受的结果。但是,由于包装的RBC(pRBC)的体积有限,大多数患者可以轻度贫血出院。我们调查了血红蛋白是否会影响急性非曲张上消化道出血患者的预后。患者和方法:我们回顾性分析了2012年1月至2014年1月期间在住院期间接受过pRBC的上消化道出血患者。排除了曲张静脉出血,恶性病变,中风或心血管疾病的患者。我们将患者分为两组,低(8?g /dL≤≤Hb10?g / dL。低Hb组的患者比高Hb组的患者具有更低的pRBC消耗量和较短的住院时间。 ?出院后直到出院后7天,血红蛋白水平仍未完全恢复;但是,大多数患者出院后45天才显示出血红蛋白恢复,两组出院后再出血率无显着差异。急性上消化道出血患者,出院血红蛋白在8至10?g / dL之间与门诊随访结果良好有关。?大多数患者在出院后45天内从贫血症中康复,没有任何严重并发症。

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