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首页> 外文期刊>Endoscopy International Open >Efficacy of single-incision needle-knife biopsy for sampling subepithelial lesions
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Efficacy of single-incision needle-knife biopsy for sampling subepithelial lesions

机译：单切口针刀活检对上皮下病变取样的功效

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Background and study aims?Single-incision needle-knife (SINK) biopsy is a diagnostic method for acquiring tissue samples for subepithelial lesions (SELs). A single linear incision is made in the overlying mucosa and tissue samples are obtained by passing conventional biopsy forceps through the opening and deep into the lesion. The aim of this study was to describe the efficacy and safety of this technique. Patients and methods?Consecutive patients who underwent SINK biopsy for an upper gastrointestinal SEL between October 2013 and September 2015 were retrospectively reviewed. Results?Forty-nine patients underwent 50 SINK biopsies. Sufficient sampling for a definite pathologic diagnosis was obtained in 42 (86?%) cases, with 91?% (40/44) having sufficient sample to perform immunohistochemistry when deemed clinically relevant. Of the 26 patients with prior non-diagnostic biopsies or FNA, a specific diagnosis was obtained in 85?% (22/26). There were no significant adverse events. Conclusions?SINK biopsy is a safe and feasible strategy for obtaining a definitive tissue diagnosis with immunohistochemistry for SELs.
机译：背景和研究目的：单切口针刀（SINK）活检是一种获取上皮下病变（SELs）组织样本的诊断方法。在上覆的粘膜上做一个线性切口，通过使常规的活检钳穿过开口并深入病灶获得组织样品。这项研究的目的是描述这种技术的有效性和安全性。患者和方法：回顾性分析2013年10月至2015年9月间接受SINK上消化道SEL活检的连续患者。结果：49例患者接受了50次SINK活检。在42（86％）的病例中，获得了足够的样本用于明确的病理学诊断，其中91％（40/44）的样本具有足够的样本以进行临床上的免疫组化分析。在26例既往没有诊断性活检或FNA的患者中，有85％（22/26）获得了明确的诊断。没有明显的不良事件。结论SINK活检是一种安全，可行的策略，可通过SELs的免疫组织化学对组织进行明确诊断。

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