Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8

Sarah Runqe; Tanja Dominko

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Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8

机译：成人成纤维细胞再生能力的获得伴随着精氨酸甲基转移酶PRMT8的上调

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Regardless of whether cancers arise as a consequence ofgenetic or epigenetic changes, the factors that controlthe balance between replicative senescence and cancerousself-renewal are of much interest as potential therapeutictargets. However, the molecular mechanisms thatregulate this perfect balance are not well understood.

机译：不管癌症是由于遗传改变还是表观遗传改变而产生，控制复制性衰老与癌性自我更新之间平衡的因素都作为潜在的治疗靶标引起了人们的极大兴趣。然而，调节这种完美平衡的分子机制还没有被很好地理解。

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《Epigenetics & Chromatin》 |2013年第1期|共页
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Sarah Runqe; Tanja Dominko;
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中图分类遗传学;
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1. The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation [J] . Louisa Hoi-Ying Lo, Rui Dong, Quanwei Lyu, Cell Reports . 2020,第10期

机译：蛋白质精氨酸甲基转移酶PRMT8和衬底G3BP1控制RAC1-PAK1信号和肌动蛋白是树突状脊柱成熟的肌动蛋白细胞骨架
2. Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons [J] . Simandi Zoltan, Pajer Krisztian, Karolyi Katalin, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2018,第35期

机译：精氨酸甲基转移酶PRMT8在衰老运动神经元中提供了细胞应激耐受性
3. Automethylation of Protein Arginine Methyltransferase 8 (PRMT8) Regulates Activity by Impeding S-Adenosylmethionine Sensitivity [J] . Myles Dillon, Heather L. Rust, Paul R. Thompson, The Journal of biological chemistry . 2013,第39期

机译：蛋白质精氨酸甲基转移酶8（PRMT8）的氨基化通过阻碍S-腺苷甲硫氨酸敏感性来调节活性
4. Regeneration competence accompanies increased expression of arginine methyltransferase PRMT8 in human adult fibroblasts [C] . Hernandez S., Dominko T. 2014 40th Annual Northeast Bioengineering Conference . 2014

机译：再生能力伴随着成年成纤维细胞中精氨酸甲基转移酶PRMT8的表达增加
5. Differential behavior of fetal and adult fibroblasts: Implications for regenerative tissue healing. [D] . Murray, Hallie Brink. 2008

机译：胎儿和成人成纤维细胞的差异行为：对再生组织愈合的影响。
6. Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8 [O] . Sarah Runqe, Tanja Dominko 2013

机译：成人成纤维细胞再生能力的获得伴随着精氨酸甲基转移酶PRMT8的上调
7. Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8 [O] . 2013

机译：成人成纤维细胞再生能力的获得伴随着精氨酸甲基转移酶PRMT8的上调

Acquisition of regeneration competence in adult fibroblasts is accompanied by upregulation of arginine methyltransferase PRMT8

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