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首页> 外文期刊>Epilepsy & Behavior Case Reports >Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes
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Anterior corpus callosotomy in patients with drug-resistant epilepsy: Invasive EEG findings and seizure outcomes

机译:耐药性癫痫患者的前体call体切开术:有创脑电图表现和癫痫发作结果

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摘要

Corpus callosotomy (CC) is used in patients with drug-resistant seizures who are not candidates for excisional surgery and failed neurostimulation. We examined ictal scalp and intracranial electroencephalogram (iEEG) recordings in 16 patients being evaluated for anterior CC alone or CC in combination with focal resection, to determine the role of the iEEG in predicting postoperative seizure outcomes. In our cohort, CC improved generalized atonic seizures and focal seizures with impaired awareness but did not alter outcomes for generalized tonic–clonic or tonic seizures. Invasive EEG prior to CC did not refine the prediction of postsurgical seizure outcomes in patients with inconclusive scalp EEG. Highlights ? Patients with drug-resistant epilepsy achieved a significant reduction of generalized atonic and focal seizures with impaired awareness following corpus callosotomy. ? The age at epilepsy diagnosis or structural pathology identified on the imaging did not predict postoperative seizure status. ? The ictal findings on invasive EEG prior to corpus callosotomy improved lateralization of seizure onset but did not predict seizure outcomes.
机译:us体切开术(CC)用于耐药性癫痫发作的患者,这些患者不适合进行切除手术和神经刺激失败。我们检查了16例接受单独前CC或CC结合局灶性切除术评估的患者的头皮和颅内脑电图(iEEG)记录,以确定iEEG在预测术后癫痫发作结果中的作用。在我们的队列中,CC改善了意识减退的全身性强直性癫痫发作和局灶性癫痫发作,但并未改变全身性强直-阵挛性或强直性癫痫发作的预后。 CC之前有创性脑电图未完善头皮脑电图未定患者术后癫痫发作预后的预测。强调 ?耐药性癫痫患者在call体切开术后明显减少了一般性无力和局灶性癫痫发作,并且意识受损。 ?在影像学上确定的癫痫诊断或结构病理学年龄不能预测术后癫痫发作状态。 ?体切开术之前侵入性脑电图的初步发现改善了癫痫发作的偏侧性,但不能预测癫痫发作的结果。

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