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Two Populations Are Better Than One

机译:两个人口比一个人口好

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It could be argued that if this is to be the place where data standards are recommended, the fundamental semiologic descriptors must be specified if a true data dictionary is to be created. What would this look like for the data element duration? First, the units would need to be specified; fortunately, seconds and minutes are universal. The next issue would be the method by which the measurement was made—the report that a time-keeping device (watch, clock) was used to document onset and termination of the seizure would be optimal. If estimation is all that is available, then the reliability of the observer—that is, medical health provider (physician, nurse, paramedic, paramedic, family member)—would need to be assessed, This estimation of time is derived from memory, which is recognized to be a complex process (9) and has only recently been tractable to direct measurement (10). Finally, it must be recognized that the observed duration is only an approximation without EEG confirmation. It is recognized that the seizure may be measured differently in the epilepsy monitoring unit (EMU) as onset and termination may be different electrically than clinically. The latter standard could certainly be applied to EMU-based studies. The current study illustrates the importance of collecting phenotypic data in a prospective, standardized manner in defining evidence-based features that are useful as risk factors and potentially giving insight into our thinking about common pathophysiologic mechanisms.
机译:可以争论的是,如果这是推荐数据标准的地方,则要创建真正的数据字典,必须指定基本的符号学描述符。数据元素持续时间将是什么样?首先,需要指定单位;幸运的是,秒和分钟是通用的。下一个问题将是进行测量的方法-使用计时设备(手表,时钟)来记录发作的报告,而癫痫发作的终止将是最佳选择。如果估计可用,则需要评估观察者的可靠性,即医疗保健提供者(医生,护士,护理人员,护理人员,家庭成员),这种时间估计是从记忆中得出的,被认为是一个复杂的过程(9),直到最近才可以直接测量(10)。最后,必须认识到,所观察到的持续时间仅是近似值,而没有EEG确认。认识到癫痫发作在癫痫监测单元(EMU)中的测量方法可能有所不同,因为发作和终止在电气上可能与临床上有所不同。后一标准当然可以应用于基于EMU的研究。当前的研究表明,以前瞻性,标准化的方式收集表型数据对于定义基于证据的特征非常重要,这些特征可用作危险因素,并有可能使我们对常见病理生理机制的想法有所了解。

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