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首页> 外文期刊>African Journal of Microbiology Research >In vitro assessment of antimicrobial potency and synergistic effects of three medicinal plants (Mentha arvensis, Carissa carandas and Calendula officinalis) extract against pathogenic bacteria
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In vitro assessment of antimicrobial potency and synergistic effects of three medicinal plants (Mentha arvensis, Carissa carandas and Calendula officinalis) extract against pathogenic bacteria

机译：三种药用植物提取物（曼陀罗，Car鱼和金盏菊）提取物对病原菌的体外抗菌作用和协同作用的体外评估

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摘要

The increased attention toward replacing chemical antimicrobials with natural remedies has led to increased studies. To prove the antimicrobial characteristics of plant extracts, their effect on infectious bacteria has to be studied in laboratory. In this study, aqueous and ethanolic extract leaves/fruits of three commonly available medicinal plants (Mentha arvensis, Carissa carandas and Calendula officinalis) individually and in combinations were tested for their antimicrobial activity against three different pathogenic bacteria (Bacillus cereus (MCCB-0143), Staphylococcus aureus (MCCB-0139) and? Escherichia coli? (MCCB-0018)) using agar disc diffusion, agar well diffusion. Among plants extracts, C. carandas fruits (Cc) and M. arvensis ethanolic extract (MaE) showed strong antimicrobial activity against E. coli (MCCB-0018). The ethanolic combination (ethanolic Calendula: Carissa: Mentha1:2:1) showed strong antimicrobial activity against B. cereus and F112 (fruits Calendula: Carissa carandas: Mentha arvensis, 1:2:1) showed significant (P < 0.05) antimicrobial activity against S. aureus (MCCB-0139). An individual and synergistic activity of ZOI ranging from 0.16-28.0 mm was active against test organism. The highest ZOI 28.0 ±1.50 was observed in Carissa fruit extracts. The study reveals that plant extracts and their combination have significant effect of antibacterial activity. The plant extract seems promising for the development of a new herbal preparation for bacterial infection.
机译：人们越来越重视用自然疗法替代化学抗菌剂，从而导致了更多的研究。为了证明植物提取物的抗菌特性，必须对它们对感染细菌的作用进行实验室研究。在这项研究中，分别测试了三种常用药用植物（曼陀罗，卡里萨斯Cal属植物和金盏菊）的水和乙醇提取物叶/果实对三种不同病原菌（蜡状芽孢杆菌（MCCB-0143））的抗菌活性。 ，金黄色葡萄球菌（MCCB-0139）和“大肠杆菌”（MCCB-0018）采用琼脂圆盘扩散法，在琼脂中充分扩散。在植物提取物中，C。carandas果实（Cc）和M. arvensis乙醇提取物（MaE）对大肠杆菌表现出很强的抗菌活性（MCCB-0018）。乙醇混合物（乙醇金盏花：Carissa：Mentha1：2：1）显示出对蜡状芽孢杆菌和F112（水果金盏花：Carissa carandas：Mentha arvensis，1：2：1）的强大抗菌活性，表现出显着（P <0.05）的抗菌活性。针对金黄色葡萄球菌（MCCB-0139）。 ZOI的个体和协同活性范围为0.16-28.0 mm，对受试生物具有活性。在Cari​​ssa水果提取物中观察到最高的ZOI 28.0±1.50。研究表明，植物提取物及其组合具有显着的抗菌活性。该植物提取物似乎有望用于细菌感染的新草药制剂的开发。

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