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Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study

机译:五种精油对口腔病原体的抗菌功效:一项体外研究

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Objectives:This study was aimed to find out the minimum inhibitory concentration (MIC) of five essential oils against oral pathogens and to find out the minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) of five essential oils against oral pathogens.Materials and Methods:The antimicrobial activities by detecting MIC and MBC/MFC of five essential oils such as tea tree oil, lavender oil, thyme oil, peppermint oil and eugenol oil were evaluated against four common oral pathogens by broth dilution method. The strains used for the study were Staphylococcus aureus ATCC 25923, Enterococcus fecalis ATCC 29212, Escherichia coli ATCC 25922 and Candida albicans ATCC 90028.Results:Out of five essential oils, eugenol oil, peppermint oil, tea tree oil exhibited significant inhibitory effect with mean MIC of 0.62 ± 0.45, 9.00 ± 15.34, 17.12 ± 31.25 subsequently. Mean MBC/MFC for tea tree oil was 17.12 ± 31.25, for lavender oil 151.00 ± 241.82, for thyme oil 22.00 ± 12.00, for peppermint oil 9.75 ± 14.88 and for eugenol oil 0.62 ± 0.45. E. fecalis exhibited low degree of sensitivity compared with all essential oils.Conclusion:Peppermint, tea tree and thyme oil can act as an effective intracanal antiseptic solution against oral pathogens.
机译:目的:本研究旨在找出五种精油对口腔病原体的最小抑菌浓度(MIC),并找出五种精油对口腔病原体的最小杀菌浓度(MBC)和最小杀菌浓度(MFC)。方法:通过肉汤稀释法,对茶树油,薰衣草油,百里香油,薄荷油和丁香酚油等五种精油进行MIC和MBC / MFC检测,以检测其对四种常见口腔病原菌的抗菌活性。用于研究的菌株为金黄色葡萄球菌ATCC 25923,粪肠球菌ATCC 29212,大肠杆菌ATCC 25922和白色念珠菌ATCC 90028。 MIC依次为0.62±0.45、9.00±15.34、17.12±31.25。茶树油的平均MBC / MFC为17.12±31.25,薰衣草油为151.00±241.82,百里香油为22.00±12.00,薄荷油为9.75±14.88,丁香酚油为0.62±0.45。结论:薄荷,茶树和百里香油可作为有效的口腔内杀菌剂治疗口腔病原体。

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