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首页> 外文期刊>Journal of Evidence-Based Integrative Medicine >In Vitro Antimicrobial Activity of Thymus vulgaris Essential Oil Against Major Oral Pathogens:
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In Vitro Antimicrobial Activity of Thymus vulgaris Essential Oil Against Major Oral Pathogens:

机译：百里香精油对主要口腔病原体的体外抗菌活性：

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摘要

The objective of present investigation was to determine antimicrobial activity of Thymus vulgaris oil on some oral pathogens. Thymus vulgaris oil was prepared by hydrodistillation and tested against 30 clinical isolates of each of Streptococcus pyogenes, Streptococcus mutans, Candida albicans, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans, prepared from related oral infections using agar disk diffusion and broth microdilution methods. Thymus vulgaris oil at concentrations of 16 to 256 μg/mL exhibited strong inhibitory activity on all clinical isolates producing inhibition zones of 7.5 to 42 mm as measured by agar disk diffusion method. Streptococcus pyogenes and Streptococcus mutans were the most sensitive isolates with minimum inhibitory concentrations of 1.9 and 3.6 μg/mL, respectively. The minimum inhibitory concentration values for C albicans, A actinomycetemcomitans, and P gingivalis were 16.3, 32, and 32 μg/mL, respectively.
机译：本研究的目的是确定百里香精油对某些口腔病原体的抗菌活性。百里香油通过加氢蒸馏制得，并用琼脂圆盘扩散法和肉汤微稀释法从相关的口腔感染中制得的化脓性链球菌，变形链球菌，变形念珠菌，白色念珠菌，牙龈卟啉单胞菌和聚集性放线菌的30种临床分离株进行了测试。浓度为16至256μg/ mL的百里香精油对所有临床分离株均表现出较强的抑制活性，通过琼脂圆盘扩散法测得其抑制区为7.5至42 mm。化脓性链球菌和变形链球菌是最敏感的分离株，其最低抑制浓度分别为1.9和3.6μg/ mL。白色念珠菌，放线菌放线菌和牙龈卟啉单胞菌的最小抑菌浓度分别为16.3、32和32μg/ mL。

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