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首页> 外文期刊>European Journal of Medicinal Plants >Phytochemical Composition and Larvicidal Activityof Ocimum canum (L.) Essential Oil againstAnopheles gambiae (Diptera: Culicidae)
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Phytochemical Composition and Larvicidal Activityof Ocimum canum (L.) Essential Oil againstAnopheles gambiae (Diptera: Culicidae)

机译：洋地黄精油对冈比亚按蚊（Diptera：Culicidae）的植物化学成分和杀幼虫活性

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Background: Malaria is a serious health problem in many countries of the world especially sub-Saharan African. Anopheles mosquito which is the vector of this disease has developed resistance against synthetic pyrethroids which are the main stay of insecticide treated bed nets. The development of insecticide resistance and side effects associated with synthetic pesticides has triggered intense research efforts towards natural products.Aim: This study aimed at investigating quality and quantity of phytochemical constituents of Ocimum canum leaf extract and determined larvicidal effect of essential oil component of this plant extract on 3rd instar larvae stage of Anopheles gambiae.Methods: The essential oil was extracted by hydro-distillation using Clevenger type apparatus. Standard methods previously described by other authors were used to determine the quality and quantity of phytochemical components of the plant and larvicidal bioassay method was used to determine the effect of essential oil of O. canum on the mosquito larva.Results: The analysis of the phytochemical revealed the presence of the following compounds: Tannin, phenol, saponin, trepenoid, alkaloid, steroid, and flavonoid, with the following quantities 22.14, 19.83, 14.08, 10.97, 8.16, 3.40 and 5.29 mg/g respectively. The mosquito larvicidal bioassay showed LC50 and LC90 values of 49.51 and 103.54×10-3 mg/ml respectively after 24 hours exposure to essential oil extract.Conclusion: The results obtained showed that the essential oil of O. canum is a promising mosquito larvicidal compound.
机译：背景：疟疾是世界上许多国家特别是撒哈拉以南非洲国家的严重健康问题。作为该病媒介的蚊子按蚊已经对合成拟除虫菊酯产生了抗药性，合成拟除虫菊酯是经过杀虫剂处理的蚊帐的主要支柱。抗药性和与合成农药相关的副作用的发展引发了对天然产物的深入研究。目的：本研究旨在调查茄子叶提取物的植物化学成分的质量和数量，并确定该植物精油成分的杀幼虫作用。方法：用Clevenger型装置通过水蒸馏法提取精油，提取冈比亚按蚊三龄幼虫。使用其他作者先前描述的标准方法来确定植物中植物化学成分的质量和数量，并使用杀幼虫生物测定方法来确定香菜油对蚊子幼虫的影响。结果：对植物化学成分进行分析揭示了以下化合物的存在：单宁，苯酚，皂苷，类萜，生物碱，类固醇和类黄酮，其含量分别为22.14、19.83、14.08、10.97、8.16、3.40和5.29 mg / g。蚊子幼虫的生化分析表明，暴露于精油提取物24小时后，LC50和LC90值分别为49.51和103.54×10-3 mg / ml。 。

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