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首页> 外文期刊>European Journal of Medicinal Plants >GC-MS Analysis of Phytocomponents andAntifungal Activities of Zanthoxylumacanthopodium DC. Collected from Manipur, India
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GC-MS Analysis of Phytocomponents andAntifungal Activities of Zanthoxylumacanthopodium DC. Collected from Manipur, India

机译：花椒GC的植物成分和抗真菌活性的GC-MS分析。从印度曼尼普尔邦收集

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Aims: The aim of this study was to evaluate the antifungal activity and phytochemical analysis of Zanthoxylum acanthopodium to validate the folklore use of this plant.Study Design: The present study was designed to evaluate the antifungal activity in different crude extracts of the Z. acanthopodium leaves followed by the characterization of chemical constituents in the extract which possess highest antifungal activity by using gas chromatography-mass spectrometry (GC-MS).Place and Duration of Study: Department of Botany, University of Delhi and Institute of Bioresources of Sustainable Development, Takyelpat Institutional Area, Imphal between December 2013 and May 2014.Methodology: The antifungal activity of Z. acanthopodium leaf extracts in three organic solvents viz. petroleum ether, ethyl acetate and chloroform were investigated against 5 strains of fungi- Aspergillus flavus, A. fumigates, A. niger, Candida albicans and C. krusei by following agar well diffusion method. The characterization of bioactive compounds in petroleum ether extract was performed using GC-MS by electron ionization in scan mode.Results: The extracts exhibited antifungal activity on two fungal species, namely C. albicans and C. krusei and the petroleum ether extract proved to possess high antifungal activity compared to the rest of the solvent extracts. The GC-MS analysis of petroleum ether extract of Z. acanthopodium leaves identified forty three compounds.Conclusion: GC-MS study highlights the existence of various bioactive compounds in Z. acanthopodium. Paulownin is found as the major compound having highest peak area and it is reported to possess antifungal property which proves that petroleum ether crude extract of Z. acanthopodium could be used as a natural antifungal.
机译：目的：本研究旨在评估花椒花椒的抗真菌活性和植物化学分析，以验证该植物的民俗用途。研究设计：本研究旨在评估花椒叶脂的不同粗提物中的抗真菌活性。然后通过气相色谱-质谱法（GC-MS）表征提取物中具有最高抗真菌活性的化学成分。研究地点和期限：德里大学植物学系和可持续发展生物资源研究所， Takyelpat机构区域，2013年12月至2014年5月间因帕尔（Imhal）。方法：刺五加叶提取物在三种有机溶剂中的抗真菌活性。通过琼脂井扩散法，研究了石油醚，乙酸乙酯和氯仿对5株真菌-黄曲霉，熏蒸曲霉，黑曲霉，白色念珠菌和克鲁斯曲霉的抗性。结果：提取物对白色念珠菌和库氏梭菌两种真菌均表现出抗真菌活性，石油醚提取物具有一定的抗真菌活性。与其他溶剂提取物相比，具有较高的抗真菌活性。刺五加叶的石油醚提取物的GC-MS分析确定了四十三种化合物。结论：GC-MS研究突出了刺五加中存在的各种生物活性化合物。泡桐素是发现的具有最大峰面积的主要化合物，并且据报道具有抗真菌特性，这证明刺五加油的石油醚粗提物可以用作天然抗真菌剂。

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