Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae

Jael Sotelo; Miguel A. Rodríguez-Gabriel

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Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae

机译：丝裂原激活的蛋白激酶Hog1是酿酒酵母中对亚砷酸盐响应的必要条件。

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Here we describe, for the first time, that budding yeast mitogen-activated protein kinase Hog1 and its upstream activators Pbs2 and Ssk1 are essential for the response to arsenite. Hog1 is rapidly phosphorylated in response to arsenite and triggers a transcriptional response that involves the upregulation of genes essential for arsenite detoxification.

机译：在这里，我们首次描述了发芽的酵母促分裂原活化蛋白激酶Hog1及其上游激活剂Pbs2和Ssk1对于亚砷酸盐的响应至关重要。 Hog1迅速响应亚砷酸盐而被磷酸化，并引发涉及亚砷酸盐解毒必不可少的基因上调的转录反应。

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《Eukaryotic cell》 |2006年第10期|共5页
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Jael Sotelo; Miguel A. Rodríguez-Gabriel;
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中图分类细胞生物学;
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1. Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae [J] . Jael Sotelo, Miguel A. Rodríguez-Gabriel Eukaryotic cell . 2006,第10期

机译：丝裂原激活的蛋白激酶Hog1是酿酒酵母中对亚砷酸盐响应的必要条件。
2. Mitogen-activated protein kinase Hog1 is activated in response to curcumin exposure in the budding yeast Saccharomyces cerevisiae [J] . Gajendra K Azad, Vikash Singh, Mayur J Thakare, BMC Microbiology . 2014,第1期

机译：有丝分裂原激活的蛋白激酶Hog1被激活以响应芽孢杆菌中的姜黄素暴露
3. The Hog1 Mitogen-Activated Protein Kinase Mediates a Hypoxic Response in Saccharomyces cerevisiae [J] . Dan Spatt, Fred Winston, Mark J. Hickman Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2011,第2期

机译：Hog1丝裂原激活的蛋白激酶介导酿酒酵母中的低氧反应。
4. Activation of Mitogen-activated Protein Kinases and Protein Kinase B/akt Signaling By Oxidative Stress in Vascular Smooth Muscle Cells: involvement in Vascular Pathophysiology [C] . Ashok K. Srivastava, Nihar R. Pandey, Antoine Blanc International Society for Heart Research.Congress . 2004

机译：血管平滑肌细胞氧化应激激活丝裂剂活化蛋白激酶和蛋白激酶B / Akt信号传导：血管病理生理学中的参与
5. Function and Signaling Specificity of the Hog1 Mitogen-Activated Protein Kinase in the Yeast Saccharomyces cerevisiae. [D] . Patterson, Jesse Christopher. 2011

机译：Hog1丝裂原激活的蛋白激酶在酵母酵母中的功能和信号特异性。
6. Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae [O] . Jael Sotelo, Miguel A. Rodríguez-Gabriel 2006

机译：丝裂原激活的蛋白激酶Hog1是酿酒酵母中对亚砷酸盐响应的必要条件。
7. Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae▿ [O] . Sotelo, Jael, Rodríguez-Gabriel, Miguel A. 2006

机译：丝裂原激活的蛋白激酶Hog1对酿酒酵母中亚砷酸盐的反应至关重要。

Mitogen-Activated Protein Kinase Hog1 Is Essential for the Response to Arsenite in Saccharomyces cerevisiae

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