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Hematopoietic growth factors in the elderly

机译:老年人造血生长因子

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The Hematopoietic System is subject to the aging process. This translates in a blunted response to Hematopoietic stress in the elderly population. The clinical use of Hematopoietic growth factors (HGFs) has helped transform the care of the elderly cancer patient. The indications for the use of hematopoietic growth factors in the elderly population are no different from the general population. In fact, given the increased susceptibility of the elderly cancer patient to treatment related morbidity and mortality, there may be even more compelling reason for the use of growth factors, to obviate complications of myelosuppression. We review the biology of aging and hematopoiesis,and the indications for the use of HGFs in the elderly.
机译:造血系统会老化。这意味着老年人对造血应激反应迟钝。造血生长因子(HGF)的临床使用已帮助改变了老年癌症患者的护理。在老年人口中使用造血生长因子的适应症与普通人群没有什么不同。实际上,考虑到老年癌症患者对与治疗相关的发病率和死亡率的敏感性增加,使用生长因子消除骨髓抑制并发症的原因可能更加令人信服。我们回顾了衰老和造血的生物学,以及在老年人中使用HGF的适应症。

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