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首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >Jianpi Bushen, a Traditional Chinese Medicine Therapy, Combined with Chemotherapy for Gastric Cancer Treatment: A Meta-Analysis of Randomized Controlled Trials
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Jianpi Bushen, a Traditional Chinese Medicine Therapy, Combined with Chemotherapy for Gastric Cancer Treatment: A Meta-Analysis of Randomized Controlled Trials

机译：健脾补肾，中医疗法与化学疗法联合治疗胃癌：一项随机对照试验的荟萃分析

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Objective. To investigate the effects of Jianpi Bushen (JPBS), a traditional Chinese medicine that is used to invigorate the spleen and tonify the kidney, combined with chemotherapy for the treatment of gastric cancer. Methods. Literature retrieval was performed in PubMed, EMBASE, Cochrane Library, MEDLINE, CNKI, Wanfang Data Information Site, and VIP from inception to October 2017. Randomized controlled trials to evaluate the effects of JPBS combined with chemotherapy were identified. The primary reported outcomes were KPS (Karnofsky Performance Status), clinical curative efficiency, immune function, blood system, and nonhematologic system. Review Manager 5.3 (RevMan 5.3) was used for data analysis, and the quality of the studies was also appraised. Results. A total of 26 studies were included with 3098 individuals. The results of the meta-analysis indicated that treatment of gastric cancer with the combination of JPBS and chemotherapy resulted in better outcomes compared to chemotherapy alone. Conclusion. Evidence from the meta-analysis suggested that JPBS combined with chemotherapy has a positive effect on gastric cancer treatment. However, additional rigorously designed and large sample randomized controlled trials are required to confirm the efficacy and safety of this treatment.
机译：目的。为了研究健脾补肾（JPBS）的作用，中药用于健脾益肾，结合化学疗法治疗胃癌。方法。从开始到2017年10月，在PubMed，EMBASE，Cochrane图书馆，MEDLINE，CNKI，Wanfang数据信息站点和VIP中进行文献检索。确定了评估JPBS联合化疗效果的随机对照试验。报告的主要结局指标为KPS（卡诺夫斯基状态），临床疗效，免疫功能，血液系统和非血液系统。使用Review Manager 5.3（RevMan 5.3）进行数据分析，并评估研究的质量。结果。共有26项研究纳入了3098名个体。荟萃分析的结果表明，与单独化疗相比，联合应用JPBS和化学疗法治疗胃癌可获得更好的疗效。结论。荟萃分析的证据表明，JPBS联合化疗对胃癌的治疗具有积极作用。但是，还需要进行额外的严格设计和大样本随机对照试验，以确认该治疗的有效性和安全性。

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