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首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >Effect ofRhizoma coptidis(Huang Lian) on Treating Diabetes Mellitus
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Effect ofRhizoma coptidis(Huang Lian) on Treating Diabetes Mellitus

机译：effect o fr Hi子哦Mac op踢DIS(Huang Lian) on treating diabetes Mel力图使

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The rapidly increasing diabetes mellitus (DM) is becoming a major public health issue globally; considerable progress has been made in the field of western hypoglycemic drug and insulin, but some shortages still exist. As one of the most important parts in complementary and alternative therapies, traditional Chinese medicine (TCM) performs a good clinical practice and is showing a bright future in the treatment of DM. TCM therapy has certain advantages of less toxicity and/or side effects, and Chinese herbal medicine which usually contains various active ingredients could provide multiple therapeutic effects. Huang Lian (Rhizoma coptidis, RC) is a herb frequently used in many traditional formulas for properties of “clearing damp-heat, quenching fire, and counteracting poison” in Asia for centuries. In this review, we summarize the application ofRCin the treatment of DM from two aspects of contents. Firstly, theoretical principles are explained, including the properties and related records aboutRCin ancient references and modern pharmacological researches and pharmacokinetics onRCand its active components. Secondly, the clinical application ofRCis mainly reviewed, such as applicable stage and syndrome, the reasonable dose range, the preparation formulations, and the toxicity and/or side effects and solutions to its adverse actions. This review provides scientific evidence about the effective components, pharmacological researches, and toxicity ofRC, as well as introducing traditional Chinese medical theory and clinical experience, in order to guide clinician to useRCmore suitably and reasonably in the clinical practice.
机译：迅速增长的糖尿病（DM）成为全球主要的公共卫生问题。在西方降糖药和胰岛素领域已经取得了相当大的进步，但是仍然存在一些不足。作为补充疗法和替代疗法中最重要的部分之一，中药（TCM）具有良好的临床实践，并且在DM的治疗方面显示出光明的未来。中药疗法具有毒性和/或副作用较小的某些优势，通常包含多种活性成分的中草药可以提供多种治疗效果。黄连（Rhizoma coptidis，RC）是一种草药，在亚洲已有数百年历史，在许多传统配方中经常使用，具有“清湿清热，消炎解毒”的特性。本文从两个方面总结了RC在糖尿病治疗中的应用。首先，对理论原理进行了解释，包括有关RC的性质和相关记录在古代参考文献中以及关于RC及其有效成分的现代药理研究和药代动力学。其次，主要回顾了RC的临床应用，如适用的阶段和综合症，合理的剂量范围，制剂，不良反应的毒性和/或副作用及其解决方案。这篇综述提供了有关RC的有效成分，药理研究和毒性的科学证据，并介绍了中医理论和临床经验，以指导临床医生在临床实践中更适当，更合理地使用RC。

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