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PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES MELLITUS, METHOD FOR PREVENTING OR TREATING DIABETES MELLITUS, AND METHOD FOR SCREENING FOR DIABETES MELLITUS THERAPEUTIC AGENT
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES MELLITUS, METHOD FOR PREVENTING OR TREATING DIABETES MELLITUS, AND METHOD FOR SCREENING FOR DIABETES MELLITUS THERAPEUTIC AGENT
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机译:用于预防或治疗糖尿病的药物组合物,用于预防或治疗糖尿病的方法以及用于筛查糖尿病的治疗剂的方法
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摘要
Provided are a pharmaceutical composition including geraniol or a pharmaceutically acceptable salt thereof as an active ingredient for use in preventing or treating diabetes mellitus, a method of preventing or treating diabetes mellitus or a complication due to diabetes mellitus of an individual, in which the method includes administering the individual with a pharmaceutical composition comprising geraniol or a pharmaceutically acceptable salt thereof as an active ingredient and inducing an olfactory stimulation to the individual using the pharmaceutical composition, and a screening method of an antidiabetic agent that may include contacting a cell expressing an olfactory receptor with a test material; measuring a level of expression of glucagon-like peptide-1 (GLP-1) secreted from the cell; and determining the test material, when the test material promotes expression of GLP-1, as a candidate material of an antidiabetic agent. In addition, a quasi-drug composition and a cosmetic composition including geraniol for uses are provided.
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