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Multifaceted role of tocotrienols in cardioprotection supports their structure: function relation

机译：生育三烯酚在心脏保护中的多方面作用支持其结构：功能关系

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Tocotrienols are a class of vitamin E which modulates several mechanisms associated with cardioprotection, anti-cancer, anti-diabetic, and neuroprotection. Unlike other Vitamin E-like compounds, tocotrienols possess inimitable properties. Quite a lot of studies have determined the cardioprotective abilities of tocotrienols and have been shown to possess novel hypocholesterolemic effects together with an ability to reduce the atherogenic apolipoprotein and lipoprotein plasma levels. In addition, tocotrienol has been suggested to have an antioxidant, anti-thrombotic, and anti-tumor effect indicating that tocotrienol may serve as an effective agent in the prevention and/or treatment of cardiovascular disease and cancer. The bioactivity exhibited is due to the structural characteristics of tocotrienols. Rich sources of tocotrienols which include rice bran, palm oil, and other edible oils exhibit protective effect against cardiovascular disorders. The conclusions drawn from the early literature that vitamin E group of compounds provides an inevitable role in cardioprotection is sustained in many more recent studies.
机译：生育三烯酚是一类维生素E，它调节与心脏保护，抗癌，抗糖尿病和神经保护有关的几种机制。与其他类似维生素E的化合物不同，生育三烯酚具有独特的性能。大量的研究确定了生育三烯酚的心脏保护能力，并显示出具有新颖的降胆固醇作用以及降低动脉粥样硬化载脂蛋白和脂蛋白血浆水平的能力。另外，已经提出生育三烯酚具有抗氧化剂，抗血栓形成和抗肿瘤作用，表明生育三烯酚可以用作预防和/或治疗心血管疾病和癌症的有效试剂。表现出的生物活性是由于生育三烯酚的结构特征。生育三烯酚的丰富来源包括米糠，棕榈油和其他食用油，对心血管疾病具有保护作用。从早期文献中得出的结论是，维生素E类化合物在心脏保护中起着不可避免的作用，这在许多最近的研究中得到了维持。

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