首页> 外文期刊>Genomics >Transcriptomic response of Drosophila melanogaster pupae developed in hypergravity ☆
【24h】

Transcriptomic response of Drosophila melanogaster pupae developed in hypergravity ☆

机译:果蝇在超重力作用下的转录反应

获取原文
           

摘要

Alteredgravitycanperturbnormaldevelopmentandinducecorrespondingchangesingeneexpression.UnderstandingthisrelationshipbetweenthephysicalenvironmentandabiologicalresponseisimportantforNASA'sspacetravelgoals.WeuseRNA-SeqandqRT-PCRtechniquestoprofilechangesinearlyemDrosophilamelanogaster/empupaeexposedtochronichypergravity(3#xA0;emg/em,orthreetimesEarth'sgravity).Duringthepupalstage,emD.melanogaster/emrelyupongravitationalcuesforproperdevelopment.Assessinggeneexpressionchangesinthepupaeunderalteredgravityconditionshelpshighlightgravity-dependentgeneticpathways.Arobusttranscriptionalresponsewasobservedinhypergravity-treatedpupaecomparedtocontrols,with1513genesshowingasignificant(q#xA0;#xA0;0.05)differenceingeneexpression.Fivemajorbiologicalprocesseswereaffected:iontransport,redoxhomeostasis,immuneresponse,proteolysis,andcuticledevelopment./ppid="sp0065"ThisoutlinestheunderlyingmolecularandbiologicalchangesoccurringinemDrosophila/empupaeinresponsetohypergravity;gravityisimportantformanybiologicalprocessesonEarth./p/div
机译:Alteredgravitycanperturbnormaldevelopmentandinducecorrespondingchangesingeneexpression.UnderstandingthisrelationshipbetweenthephysicalenvironmentandabiologicalresponseisimportantforNASA'sspacetravelgoals.WeuseRNA-SeqandqRT-PCRtechniquestoprofilechangesinearly 黑腹果蝇 pupaeexposedtochronichypergravity(3#XA0; ,orthreetimesEarth'sgravity).Duringthepupalstage,果蝇 relyupongravitationalcuesforproperdevelopment.Assessinggeneexpressionchangesinthepupaeunderalteredgravityconditionshelpshighlightgravity-dependentgeneticpathways.Arobusttranscriptionalresponsewasobservedinhypergravity-treatedpupaecomparedtocontrols,with1513genesshowingasignificant(q#XA0; LT;#XA0; 0.05)differenceingeneexpression.Fivemajorbiologicalprocesseswereaffected:iontransport,redoxhomeostasis,免疫反应,蛋白水解,andcuticledevelopment Thisoutlinestheunderlyingmolecularandbiologicalchangesoccurringin。果蝇的果蝇反应性重力;重力地球上任何重要的生物过程。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号