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首页> 外文期刊>Genomics Insights >Comparative Genomics of Bacillus species and its Relevance in Industrial Microbiology:
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Comparative Genomics of Bacillus species and its Relevance in Industrial Microbiology:

机译：芽孢杆菌属物种的比较基因组学及其在工业微生物学中的相关性：

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摘要

With the advent of high throughput sequencing platforms and relevant analytical tools, the rate of microbial genome sequencing has accelerated which has in turn led to better understanding of microbial molecular biology and genetics. The complete genome sequences of important industrial organisms provide opportunities for human health, industry, and the environment. Bacillus species are the dominant workhorses in industrial fermentations. Today, genome sequences of several Bacillus species are available, and comparative genomics of this genus helps in understanding their physiology, biochemistry, and genetics. The genomes of these bacterial species are the sources of many industrially important enzymes and antibiotics and, therefore, provide an opportunity to tailor enzymes with desired properties to suit a wide range of applications. A comparative account of strengths and weaknesses of the different sequencing platforms are also highlighted in the review.
机译：随着高通量测序平台和相关分析工具的出现，微生物基因组测序的速度加快了，这反过来又使人们对微生物分子生物学和遗传学有了更好的了解。重要工业有机体的完整基因组序列为人类健康，工业和环境提供了机会。芽孢杆菌属是工业发酵中的主要动力。如今，已有数种芽孢杆菌属的基因组序列可供使用，该属的比较基因组学有助于理解它们的生理学，生物化学和遗传学。这些细菌物种的基因组是许多工业上重要的酶和抗生素的来源，因此，提供了一个机会来定制具有所需特性的酶，以适应广泛的应用。审查中还重点介绍了不同测序平台的优缺点的比较。

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